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aneurysm

Aneurysm

An aneurysm or aneurism (from Greek: ἀνεύρυσμα, aneurusma, “dilation”, from ἀνευρύνειν, aneurunein, “to dilate”) is a localized, blood-filled balloon-like bulge in the wall of a blood vessel.

Aneurysms can occur in any blood vessel with examples including aneurysms of the circle of Willis in the brain, aortic aneurysms affecting the thoracic aorta, and abdominal aortic aneurysms. Aneurysms can also occur within the heart itself. As an aneurysm increases in size, the risk of rupture increases.

A ruptured aneurysm can lead to bleeding and subsequent hypovolemic shock, leading to death. Aneurysms are a result of a weakened blood vessel wall, and can be a result of a hereditary condition or an acquired disease.

The most frequent location is the arterial bifurcation.

Types

By morphology

According to multilobulation, presence of a daughter sac, and presence of a small basal outpouching (SBO).

Parts

Associations

Aneurysms associated with arteriovenous malformations (AVM) are well represented in the literature. Their exact etiology is poorly understood, but likely global hemodynamic changes coupled with vascular wall pathology play into their formation. Flow-related and intranidal aneurysms, in particular, appear to have an increased risk for hemorrhagic presentation. Treatment strategies for these aneurysms are particularly challenging 1).

Treatment

Evolving endovascular technologies need to be integrated into the microsurgical management of aneurysms. Multimodality approaches are best used with complex aneurysms in which conventional therapy with a single modality has failed. Revascularization remains a unique surgical contribution to the overall management of aneurysms with which current endovascular techniques cannot be used. Multimodality management should be considered an elegant addition to the therapeutic armamentarium that, through simplification and increased safety, improves the treatment of complex aneurysms beyond what is achievable by performing clipping or coiling alone 2).

Aneurysm models

1)
He L, Gao J, Thomas AJ, Fusco MR, Ogilvy CS. Disappearance of a ruptured distal flow-related aneurysm after AVM nidal embolization. World Neurosurg. 2015 Jun 10. pii: S1878-8750(15)00714-7. doi: 10.1016/j.wneu.2015.05.065. [Epub ahead of print] PubMed PMID: 26072456.
2)
Lawton MT, Quinones-Hinojosa A, Sanai N, Malek JY, Dowd CF. Combined microsurgical and endovascular management of complex intracranial aneurysms. Neurosurgery. 2008 Jun;62(6 Suppl 3):1503-15. doi: 10.1227/01.neu.0000333814.02649.a0. PubMed PMID: 18695569.
aneurysm.txt · Last modified: 2016/02/03 10:07 (external edit)