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antiplatelet

Antiplatelet

Drugs that interfere with platelet function can be classified into 3 categories:

Those that prevent cardiovascular disease (primary prevention), those that treat an acute disease, and those that treat a chronic disease (secondary prevention)

There are both oral (taken by mouth) and intravenous (given through a vein) drugs that inhibit platelet function and are used to treat patients with cardiac and cerebrovascular diseases.

Classification

The class of antiplatelet drugs include:

Irreversible cyclooxygenase inhibitors Aspirin Triflusal (Disgren) Adenosine diphosphate (ADP) receptor inhibitors Clopidogrel (Plavix) Prasugrel (Effient) Ticagrelor (Brilinta) Ticlopidine (Ticlid) Phosphodiesterase inhibitors Cilostazol (Pletal) Protease-activated receptor-1 (PAR-1) antagonists Vorapaxar (Zontivity) Glycoprotein IIB/IIIA inhibitors (intravenous use only) Abciximab (ReoPro) Eptifibatide (Integrilin) Tirofiban (Aggrastat) Adenosine reuptake inhibitors Dipyridamole (Persantine) Thromboxane inhibitors Thromboxane synthase inhibitors Thromboxane receptor antagonists Terutroban


A platelet count of less than 135,000/µL in patients on antiplatelet therapy is predictive of both radiographic and clinical worsening. This is a clinically relevant target intended to help tailor and improve management in patients on antiplatelet therapy.

see Dual antiplatelet therapy

antiplatelet.txt · Last modified: 2017/10/17 15:00 by administrador