The outcome of Bladder cancer intracranial metastases remains guarded. Factors associated with improved survival include intracranial resection. Future, prospective work is needed to further define optimal management 1).
Results indicate that radiation therapy alone is inadequate treatment. Therefore, when possible, Mahmoud-Ahmed et al., advocate more effective treatment by combining radiation therapy with other treatment modalities, as recommended in ongoing clinical trials 2).
Rosenstein et al., recommend that patients with solitary brain lesions and good performance status be aggressively managed with surgical resection and postoperative radiation therapy 3).