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escherichia_coli

Escherichia coli

Escherichia coli (E. coli) is the most common causative bacteria of neonatal meningitis, but hematogenous intracranial E. coli infection is rare in adults. Moreover, intracranial abscess formation owing to E. coli, including brain abscesses and subdural empyema formation, is extremely rare.

The prognosis of patients with E. coli-associated intracranial abscess is usually poor. Advanced age and immunosuppression may be potent risk factors for intracranial abscess formation owing to the hematogenous spread of E. coli 1).

Th1 and Th17 cytokines were significantly elevated in Gram positive (Staphylococcus aureus and Streptococcus intermedius) and Th2 cytokine (IL-10) in Gram negative (Bacteroides fragilis and Escherichia coli) infections 2).

1)
Akuzawa N, Osawa T, Totsuka M, Hatori T, Imai K, Kitahara Y, Kurabayashi M. Secondary brain abscess following simple renal cyst infection: a case report. BMC Neurol. 2014 Jun 16;14:130. doi: 10.1186/1471-2377-14-130. PubMed PMID: 24934996; PubMed Central PMCID: PMC4070354.
2)
Bajpai A, Prasad KN, Mishra P, Singh AK, Gupta RK, Ojha BK. Distinct cytokine pattern in response to different bacterial pathogens in human brain abscess. J Neuroimmunol. 2014 Aug 15;273(1-2):96-102. doi: 10.1016/j.jneuroim.2014.05.009. Epub 2014 May 24. PubMed PMID: 24910026.
escherichia_coli.txt · Last modified: 2016/02/16 14:30 (external edit)