These cystic lesions are congenital.
Arachnoid cysts account for only 1% of all intracranial space-occupying lesions.
Intracranial cysts are classified as supratentorial, infratentorial, and supra-infratentorial (tentorial notch) 1).
Supratentorial are divided into:
Quadrigeminal plate cistern
Many theories have been postulated for etiopathogenesis of arachnoid cysts. Various hypotheses are: entrapment of CSF in a diverticulum; CSF flow changes leading to arachnoid cell layer tears during the formation of various cisternae; during embryological separation (at around 15th week of gestation) of arachnoid from the dura mater 2).
ACs with mass effect are detected frequently in asymptomatic patients. Conversely, symptomatic patients may present without imaging signs of a focal mass effect that emphasizes the difficulty of relying on imaging as the sole criteria in surgical selection.
Although it is generally accepted that asymptomatic or paucisymptomatic cysts do not require surgical treatment, there is no consensus on the therapeutic approach of choice in symptomatic cases 3).
Acetazolamide known to reduce CSF production, might mimic surgical decompression and therefore could serve as a decision-making tool in patients with ACs.
A total of 103 patients with radiographically proven ACs were initially identified. Twenty (19.4%) were symptomatic and underwent a trial of oral AZM. Data were collected meeting inclusion/exclusion criteria for this cohort study and analyzed retrospectively/prospectively. Results Overall, 17 patients were able to tolerate the AZM and had at least some subjective improvement in their symptoms during the AZM challenge and underwent surgical therapy. Surgery was beneficial in 16 patients (94.1%). Following surgery, symptoms resolved in 13 patients (76.5%) and improved in 3 (17.6%).
The AZM challenge may support the clinical decision to recommend surgery in those patients whose symptoms improve during AZM therapy 4).
Craniotomy and fenestration of membranes is one of the main treatment options for symptomatic arachnoid cysts. Open surgery advantages include, direct inspection of the cyst, biopsy sampling, fenestration in multilocular cysts and, in certain locations, cyst communication to basal cisterns 5).
Surgery for AC can be performed with a fairly low risk of complications and yields significant improvement in quality of life correlated to postoperative improvement in headache and dizziness. These findings may justify a more liberal approach to surgical treatment for AC 6).
Spontaneous intracystic hemorrhage in an arachnoid cyst is a rare complication (although hemorrhagic arachnoid cyst is well known in the clinical setting of trauma), which may present with symptoms of raised intracranial pressure (headache, vomiting, altered sensorium) or focal neurological deficits depending on the location and is an indication for surgery 7) 8).
Although complications such as intracystic, subdural, and extradural hematomas are well known after a trauma, spontaneous hemorrhage in an arachnoid cyst is a rare and serious complication with atypical imaging features on cross-sectional imaging and only less than ten cases are documented in the literature 9).
Surgery can be performed with a fairly low risk of complications and yields significant improvement in quality of life correlated to postoperative improvement in headache and dizziness. These findings may justify a more liberal approach to surgical treatment 10).
There is currently no consensus on the safety of sports participation for patients with an intracranial arachnoid cyst (AC).
A survey was prospectively administered to 185 patients with ACs during a 46-month period at a single institution. Cyst size and location, treatment, sports participation, and any injuries were recorded. Eighty patients completed at least 1 subsequent survey following their initial entry into the registry, and these patients were included in a prospective registry with a mean prospective follow-up interval of 15.9 ± 8.8 months.
A total 112 patients with ACs participated in 261 sports for a cumulative duration of 4410 months or 1470 seasons. Of these, 94 patients participated in 190 contact sports for a cumulative duration of 2818 months or 939 seasons. There were no serious or catastrophic neurological injuries. Two patients presented with symptomatic subdural hygromas following minor sports injuries. In the prospective cohort, there were no neurological injuries
Permanent or catastrophic neurological injuries are very unusual in AC patients who participate in athletic activities. In most cases, sports participation by these patients is safe 11).