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intramedullary_spinal_cord_tumor

Intramedullary spinal cord tumor

Astrocytomas are the most common intramedullary spinal cord tumor in pediatric and adolescent patients and the incidence decreases with age. There are very few cases of spinal pilocytic astrocytomas (World Health Organization grade 1) reported after the fourth decade 1).

see Intramedullary astrocytoma.

Epidemiology

Intramedullary spinal cord tumors (IMSCT) are rare lesions and constitute only 4-10% of all primary central nervous system tumors 2) 3).

IMSCTs are less common in adults than in children and constitute 20% and 35%, respectively of all intraspinal tumors 4) 5) 6) 7).

The most commonly occurring intramedullary neoplasm is spinal cord ependymoma followed by spinal cord astrocytoma and other lesions 8) 9) 10) 11).

1)
Harraher CD, Vogel H, Steinberg GK. Spinal pilocytic astrocytoma in an elderly patient. World Neurosurg. 2013 May-Jun;79(5-6):799.E7-9. doi: 10.1016/j.wneu.2011.10.033. Epub 2011 Nov 1. PubMed PMID: 22120566.
2) , 4)
Klekamp J, Samii M. Surgery of spinal tumors. Berlin – Heidelberg: Springer; 2007.
3) , 5) , 8)
Manzano G, Green BA, Vanni S, Levi AD. Contemporary management of adult intramedullary spinal tumors – pathology and neurological outcomes related to surgical resection. Spinal Cord. 2008;46(8):540–546. doi: 10.1038/sc.2008.51.
6)
Antoniadis G, Engelhardt M, Börm W, Richter HP, Rath SA. Spinale intramedulläre Tumoren. Wann ist die operative Behandlung angezeigt? Nervenarzt. 2005;76(2):186–192. doi: 10.1007/s00115-004-1788-2.
7)
Raco A, Esposito V, Lenzi J, Piccirilli M, Delfini R, Cantore G. Long-term follow-up of intramedullary spinal cord tumors: a series of 202 cases. Neurosurgery. 2005;56(5):972–981.
9)
McCormick PC, Torres R, Post KD, Stein BM. Intramedullary ependymoma of the spinal cord. J Neurosurg. 1990;72(4):523–532. doi: 10.3171/jns.1990.72.4.0523.
10)
Minehan KJ, Brown PD, Scheithauer BW, Krauss WE, Wright MP. Prognosis and treatment of spinal cord astrocytoma. Int J Radiat Oncol Biol Phys. 2009;73(3):727–733. doi: 10.1016/j.ijrobp.2008.04.060.
11)
Patil CG, Patil TS, Lad SP, Boakye M. Complications and outcomes after spinal cord tumor resection in the United States from 1993 to 2002. Spinal Cord. 2008;46(5):375–379. doi: 10.1038/sj.sc.3102155.
intramedullary_spinal_cord_tumor.txt · Last modified: 2017/09/09 10:59 by administrador