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Neural cell adhesion molecule L1



Transmembrane protein member of the L1 protein family, encoded by the L1CAM gene. This protein, of 200-220 kDa, is a neuronal cell adhesion molecule with a strong implication in cell migration, adhesion, neurite outgrowth, myelination and neuronal differentiation.

It also plays a key role in treatment-resistant cancers due to its function. It was firstly identified in 1984 by Melitta Schachner who found the protein in post-mitotic mice neurons.

l1cam.txt · Last modified: 2017/11/22 18:27 by administrador