Over the course of decades, Neurovascular compression (NVC) has become established as the cause of nearly all cases of classic or typical TN, HFS, and glossopharyngeal neuralgia (GPN) when strict diagnostic criteria are applied. These conditions are also amenable to high rates of cure by the atraumatic alleviation of culprit vascular compression via Jannetta’s MVD procedure. However, the NVC theory has also been invoked by some as a potential cause of other conditions such as non-episodic facial pain (e.g., type 2 TN), Bell’s palsy, tinnitus, vertigo, hypertension, and diabetes.
see also Hemilaryngopharyngeal spasm.
Evidence of an association between these conditions and culprit vascular compression is less robust, and MVD surgery has not been generally accepted as effective in their treatment. There remains an appropriately great burden of proof when proposing an NVC etiology, just as Jannetta faced 1).
A case of posterior cerebral artery aneurysm, which caused the isolated trigeminal neuralgia in a 48-year-old woman, was operated on through microvascular decompression and the aneurysm was wrapped 4).