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Nicardipine for aneurysmal subarachnoid hemorrhage

Nicardipine may be given to prevent cerebral vasospasm after aneurysmal subarachnoid hemorrhage with Aggressive Cisternal Clot Removal 1).

Park et al., treated forty-four vessels in 18 patients. All vessels treated demonstrated angiographic improvement in the degree of vasospasm. TCD demonstrated significant decreases in peak systolic velocity after treatment. Neurological improvement was seen in about 42% of the patients after treatment. No significant changes in blood pressure or signs of pulmonary edema or renal dysfunction 2).

see Intraventricular nicardipine.

Ota N, Matsukawa H, Kamiyama H, Tsuboi T, Noda K, Hashimoto A, Miyazaki T, Kinoshita Y, Saito N, Tokuda S, Kamada K, Tanikawa R. Preventing Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage with Aggressive Cisternal Clot Removal and Nicardipine. World Neurosurg. 2017 Nov;107:630-640. doi: 10.1016/j.wneu.2017.08.088. Epub 2017 Aug 24. PubMed PMID: 28843762.
Park ES, Kim DW, Kang SD. Endovascular Treatment of Symptomatic Vasospasm after Aneurysmal Subarachnoid Hemorrhage: A Three-year Experience. J Cerebrovasc Endovasc Neurosurg. 2017 Sep;19(3):155-161. doi: 10.7461/jcen.2017.19.3.155. Epub 2017 Sep 30. PubMed PMID: 29159148; PubMed Central PMCID: PMC5680078.
nicardipine_for_aneurysmal_subarachnoid_hemorrhage.txt · Last modified: 2018/04/06 12:59 by administrador