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postherpetic_neuralgia

Postherpetic neuralgia

Postherpetic neuralgia is a nerve pain.

Etiology

Postherpetic neuralgia (PHN) results from injury to the nerves system caused by varicella zoster virus during shingles infection 1).

The neuralgia typically begins when the herpes zoster vesicles have crusted over and begun to heal, but can begin in the absence of herpes zoster—a condition called zoster sine herpete (see Herpes zoster).

Patients with postherpetic neuralgia (PHN) always suffer persistent and severe breakthrough pain (BTP) which may arise from nerve changes virus affection or immune response. BTP is characterized by brief duration (median 30 min), a severe intensity, rapid onset (less than 3 minutes), and daily frequency (more than 4 episodes per day) 2).

Clinical

Typically, the neuralgia is confined to a dermatomic area of the skin, and follows an outbreak of herpes zoster (commonly known as shingles) in that same dermatomic area.

Treatment

1)
Park H. G., Park P. G., Kim W. J., et al. Ultrasound-assisted mental nerve block and pulsed radiofrequency treatment for intractable postherpetic neuralgia: three case studies. Korean Journal of Pain. 2014;27(1):81–85. doi: 10.3344/kjp.2014.27.1.81.
2)
Zeppetella G., Ribeiro M. D. C. Pharmacotherapy of cancer-related episodic pain. Expert Opinion on Pharmacotherapy. 2003;4(4):493–502. doi: 10.1517/14656566.4.4.493.
postherpetic_neuralgia.txt · Last modified: 2018/01/24 09:41 by administrador