Several methods have been created to aid both neurosurgeons and neuroradiologists in precisely localizing the precentral gyrus. One of them consists of recognizing the intersection between the superior frontal sulcus and the precentral sulcus, being the motor hand area at the same sagittal plane on the precentral gyrus 1) 2).
The intersectional point between the superior frontal sulcus and precentral sulcus (*) is the invagination base of the knob on the precentral gyrus
Direct cortical stimulation studies and functional magnetic resonance imaging studies have demonstrated that the precentral gyrus lodges the motor primary cortex and the second curvature of the central sulcus, which corresponds to the knob-like form in the precentral gyrus, are specifically associated with contralateral motor hand skills.
Brain surface reformatted imaging improves the diagnostic accuracy of standard anatomical MR imaging for localizing superficial brain lesions in relation to the precentral gyrus. The complementary use of this technique with standard two-dimensional imaging is supported by the fast and simple postprocessing technique and may provide useful information for preoperative surgical planning 3).
Garcia Santos et al aimed to investigate whether magnetic resonance spectroscopy (MRS) metabolite ratios change in the precentral gyrus of patients with amyotrophic lateral sclerosis (ALS) after spinal cord surgical injection of bone marrow mononuclear cells, as well as their relationship with disability and survival and demosnstrates that spinal cord injection of stem cells shows metabolic improvement in the brain that might be related to longer survival and less disability 4).