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septum_pellucidum

Septum pellucidum

(also called the septum Pellucidum), and not to be confused with the medial septum, is a thin, triangular, vertical membrane separating the anterior horns of the left and right lateral ventricles of the brain.

It runs as a sheet from the corpus callosum down to the fornix.

The septum pellucidum consists of two laminae of both white and gray matter. During fetal development, there is a space between the two laminae called the cavum septum pellucidum, which disappears during infancy in most individuals.

Liss and Mervis 1) described three variations of the septum pellucidum. The first variation (50%) is the single midline membrane with an ependymal lining on each ventricular surface. The second variation (25%) consists of two separate but closely apposed leaves that delineate a potential space. The third variation (25%) is the cavum septum pellucidum in which the leaves of the septum are visibly separated by a space of variable size. Congenital perforations of the septum pellucidum may be present in any of these variations. These perforations characteristically have smooth margins and may be single or multiple 2).


The septum pellucidum is the anatomic site of origin of a spectrum of uncommon neuroepithelial tumors that include central neurocytoma, subependymoma, and low-grade glioneuronal tumors.

1)
Liss L, Mervis L: The ependymal lining of the cavum septi pellucidi: a histological and histochemical study. J Neuropathol Exp Neurol 23: 355–367, 1964
2)
VanWagenen WP, Aird RB: Dilatations of the cavity of the septum pellucidum and cavum vergae. Report of cases. Am J Cancer 20: 539–557, 1934
septum_pellucidum.txt · Last modified: 2019/01/09 16:30 by administrador