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stereoelectroencephalography_complications

Stereoelectroencephalography complications

In a systematic review of stereoelectroencephalography complications, thirty-five major complications (including 4 fatalities) were reported among 4,000 patients (0.8%) implanted with 33,000 electrodes 1).

SEEG has low associated complications, particularly regarding hemorrhage and infection 2).


Serletis et al., published wound infection (0.08%), hemorrhagic complications (0.08%), and a transient neurological deficit (0.04%) in a total of 5 patients (2.5%). One patient (0.5%) ultimately died due to intracerebral hematoma directly ensuing from SEEG electrode placement 3).


In the Cardinale et al., published series the major complication rate was 12 of 500 (2.4%), including 1 death for indirect morbidity. Median entry point localization error was 1.43 mm (interquartile range, 0.91-2.21 mm) with the traditional workflow and 0.78 mm (interquartile range, 0.49-1.08 mm) with the new one (P < 2.2 × 10). Median target point localization errors were 2.69 mm (interquartile range, 1.89-3.67 mm) and 1.77 mm (interquartile range, 1.25-2.51 mm; P < 2.2 × 10), respectively. 4).


Guénot et al had no general or neurologic complication occurred during the procedures. Two transient postprocedure side effects, consisting of paresthetic sensations in the mouth and mild apraxia of the hand, were observed 5).


In 10 patients that underwent this procedure, there were no derived complications 6).


The total complication rate was 4% in One hundred patients that underwent 101 robot-assisted SEEG procedures 7).


In the series of De Almeida et al., bilateral exploration of the temporal lobes has a morbidity rate of approximately 1%. A higher risk of hematomas occurs with the implantation of four or more electrodes in the frontal lobes 8).

1)
Cardinale F, Casaceli G, Raneri F, Miller J, Lo Russo G. Implantation of Stereoelectroencephalography Electrodes: A Systematic Review. J Clin Neurophysiol. 2016 Dec;33(6):490-502. PubMed PMID: 27918344.
2)
Yang M, Ma Y, Li W, Shi X, Hou Z, An N, Zhang C, Liu L, Yang H, Zhang D, Liu S. A Retrospective Analysis of Stereoelectroencephalography and Subdural Electroencephalography for Preoperative Evaluation of Intractable Epilepsy. Stereotact Funct Neurosurg. 2017 Jan 14;95(1):13-20. doi: 10.1159/000453275. [Epub ahead of print] PubMed PMID: 28088805.
3)
Serletis D, Bulacio J, Bingaman W, Najm I, González-Martínez J. The stereotactic approach for mapping epileptic networks: a prospective study of 200 patients. J Neurosurg. 2014 Nov;121(5):1239-46. doi: 10.3171/2014.7.JNS132306. PubMed PMID: 25148007.
4)
Cardinale F, Cossu M, Castana L, Casaceli G, Schiariti MP, Miserocchi A, Fuschillo D, Moscato A, Caborni C, Arnulfo G, Lo Russo G. Stereoelectroencephalography: surgical methodology, safety, and stereotactic application accuracy in 500 procedures. Neurosurgery. 2013 Mar;72(3):353-66; discussion 366. doi: 10.1227/NEU.0b013e31827d1161. PubMed PMID: 23168681.
5)
Guénot M, Isnard J, Ryvlin P, Fischer C, Mauguière F, Sindou M. SEEG-guided RF thermocoagulation of epileptic foci: feasibility, safety, and preliminary results. Epilepsia. 2004 Nov;45(11):1368-74. PubMed PMID: 15509237.
6)
Narváez-Martínez Y, García S, Roldán P, Torales J, Rumià J. [Stereoelectroencephalography by using O-Arm(®) and Vertek(®) passive articulated arm: Technical note and experience of an epilepsy referral centre]. Neurocirugia (Astur). 2016 Nov - Dec;27(6):277-284. doi: 10.1016/j.neucir.2016.05.002. Spanish. PubMed PMID: 27345416.
7)
González-Martínez J, Bulacio J, Thompson S, Gale J, Smithason S, Najm I, Bingaman W. Technique, Results, and Complications Related to Robot-Assisted Stereoelectroencephalography. Neurosurgery. 2016 Feb;78(2):169-80. doi: 10.1227/NEU.0000000000001034. PubMed PMID: 26418870.
8)
De Almeida AN, Olivier A, Quesney F, Dubeau F, Savard G, Andermann F. Efficacy of and morbidity associated with stereoelectroencephalography using computerized tomography–or magnetic resonance imaging-guided electrode implantation. J Neurosurg. 2006 Apr;104(4):483-7. PubMed PMID: 16619650.
stereoelectroencephalography_complications.txt · Last modified: 2017/01/16 11:31 (external edit)