From a retrospective study of 412 thoracolumbar injury, Francis Denis introduced the concept of middle column or middle osteoligamentous complex between the traditionally recognized posterior ligamentous complex and the anterior longitudinal ligament 1).

Percutaneous balloon compression trigeminal rhizotomy, has been used to treat trigeminal neuralgia since 1983.

In 1983, as crystal-based neodymium-doped yttrium aluminum garnet Nd:YAG laser was introduced for tissue ablation, and some studies followed of laser ablation for brain tumors 2) 3) 4) 5).

The polymerase chain reaction (PCR) is a technology in molecular biology used to amplify a single copy or a few copies of a piece of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence.

Developed in 1983 by Kary Mullis, PCR is now a common and often indispensable technique used in medical and biological research labs for a variety of applications.

These include DNA cloning for sequencing, DNA-based phylogeny, or functional analysis of genes; the diagnosis of hereditary diseases; the identification of genetic fingerprints (used in forensic sciences and DNA paternity testing); and the detection and diagnosis of infectious diseases. In 1993, Mullis was awarded the Nobel Prize in Chemistry along with Michael Smith for his work on PCR.

Introduced in 1983, Cotrel Dubousset Instrumentation is a treatment approach to scoliosis. Unlike Harrington rods, this treatment is more than just an osteodistraction mechanism and allows correction of some of the features of scoliosis untreatable by Harrington rods, such as rib hump.

Denis F. The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. Spine (Phila Pa 1976). 1983 Nov-Dec;8(8):817-31. PubMed PMID: 6670016.
S.G. Bown, Phototherapy in tumors, World Journal of Surgery, 7 (1983) 700-709.
K. Sugiyama, T. Sakai, I. Fujishima, H. Ryu, K. Uemura, T. Yokoyama, Stereotactic interstitial laser-hyperthermia using Nd-YAG laser, Stereotactic and functional neurosurgery, 54-55 (1990) 501-505.
M. Bettag, F. Ulrich, R. Schober, G. Furst, K.J. Langen, M. Sabel, J.C. Kiwit, Stereotactic laser therapy in cerebral gliomas, Acta neurochirurgica. Supplementum, 52 (1991) 81-83.
F.X. Roux, L. Merienne, B. Leriche, S. Lucerna, B. Turak, B. Devaux, J.P. Chodkiewicz, Laser interstitial thermotherapy in stereotactical neurosurgery, Lasers in Medical Science, 7 (1992) 121-126.
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