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In 1994 Dubousset 1) described the concept of “cone of economy” which is a range of spinal alignment in which a minimum of muscle activity is required to maintain balance.

The strategy of convection-enhanced delivery was developed by Bobo et al. to deliver drugs directly into tumors and surrounding brain through the interstitial space 2).

In July 1994 Ali Krisht joined Ossama Al Mefty and Yasargil as staff of the Department of Neurosurgery, at the University of Arkansas.

Dubousset J, Weinstein SL. Three-dimensional anal- ysis of the scoliotic deformity. In: The pediatric spine: Principles and practice. New York, NY: Raven Press; 1994:479–496
Bobo RH, Laske DW, Akbasak A, Morrison PF, Dedrick RL, Oldfield EH. Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci U S A. 1994 Mar 15;91(6):2076-80. PubMed PMID: 8134351; PubMed Central PMCID: PMC43312.
1994.txt · Last modified: 2019/10/20 11:54 by administrador