1993-1995

In 1994 Dubousset ¹⁾ described the concept of “cone of economy” which is a range of spinal alignment in which a minimum of muscle activity is required to maintain balance.

The strategy of convection-enhanced delivery was developed by Bobo et al. to deliver drugs directly into tumors and surrounding brain through the interstitial space ²⁾.

In July 1994 Ali Krisht joined Ossama Al Mefty and Yasargil as staff of the Department of Neurosurgery, at the University of Arkansas.