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In ALK+ NSCLC, the ALK gene undergoes a rearrangement, called a translocation, within the chromosome to create a fusion between ALK and another gene 1).

Solomon B, Wilner KD, Shaw AT. Current status of targeted therapy for anaplastic lymphoma kinase-rearranged non-small cell lung cancer. Clin Pharmacol Ther. 2014;95:15-23. PMID: 24091716
alk_gene.txt · Last modified: 2018/03/25 22:37 by administrador