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Aminoglutethimide (Cytadren®): inhibits the initial enzyme in the synthesis of steroids from cholesterol. Normalizes urinary free cortisol in ≈ 50% of cases.

Side effects: dose-dependent reversible effects include sedation, anorexia, nausea, rash and hypothyroidism (due to interference with thyroid hormone synthesis).

aminoglutethimide.txt · Last modified: 2019/06/13 23:18 by administrador