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angiosarcoma

Angiosarcoma

Masson’s vegetant intravascular hemangioendothelioma 1) : an uncommon, usually benign lesion that may rarely involve the neuraxis (including intracranial occurrence). Not definitely neoplastic. Organizing thrombi develop endothelialized projections into the vessel lumen. Must be distinguished from other conditions such as angiosarcoma


Angiosarcomas (ASs) are rare malignant vascular tumours, which only occasionally occur in the spine. The prognosis is generally poor due to rarity of the condition as well as lack of data of treatment options.

Case reports

Pülhorn et al., present the case of a 75-year old man with a primary angiosarcoma of C2 and C3 who underwent occipito-cervical (to C6) fixation. A first biopsy did not result in a diagnosis and a further anterior approach with repeat biopsy had to be undertaken. The patient received adjuvant radiotherapy and at 6-month follow-up there was no radiological progression of the angiosarcoma. ASs are a rare condition and due to paucity of data relating to management cases should be reported to aid understanding and development of guidelines for diagnosis and treatment 2).

1)
Wen DY, Hardten DR, Wirtschafter JD, et al. Elevated Intracranial Pressure from Cerebral Venous Obstruction by Masson's Vegetant Intravascular Hemangioendothelioma. J Neurosurg. 1991; 75:787–790
2)
Pülhorn H, Elliot T, Clark J, Gonzalvo A. Case report: Angiosarcoma of the cervical spine. J Clin Neurosci. 2017 Aug 1. pii: S0967-5868(17)30334-X. doi: 10.1016/j.jocn.2017.07.018. [Epub ahead of print] PubMed PMID: 28778802.
angiosarcoma.txt · Last modified: 2018/12/13 20:54 by administrador