Atypical meningioma (AM)

Atypical meningioma (WHO Grade II) comprise a heterogeneous group of tumors, with histopathology delineated under the guidance of the WHO and a spectrum of clinical outcomes.

In the World Health Organization Classification of Tumors of the Central Nervous System 2016 notable changes include the addition of brain invasion as a criterion for atypical meningioma 1).

Intracranial atypical meningiomas

Spinal atypical meningiomas

Approximately 15-20% of meningiomas are atypical, meaning that the tumor cells do not appear typical or normal. Atypical meningiomas are neither malignant (cancerous) nor benign, but may become malignant.

see Atypical meningioma diagnosis.

Typical meningioma: Usually noninvasive, but histology is needed for definitive diagnosis.

Dural metastasis: Extracranial neoplasm is usually known (eg, neuroblastoma).

Lymphoma: Often lytic bone lesion with epidural and extracranial components.

Ewing sarcoma: Often osseous laminated periosteal reaction.

see Atypical meningioma treatment.

see Atypical meningioma outcome.

Atypical meningioma case series.

Atypical meningioma case reports.

Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol. 2016 Jun;131(6):803-20. doi: 10.1007/s00401-016-1545-1. Review. PubMed PMID: 27157931.
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  • Last modified: 2020/03/08 12:19
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