Azygos anterior cerebral artery

An azygos anterior cerebral artery is an uncommon to rare variant of the circle of Willis where the two A1 segment of the anterior cerebral artery (ACA) join to form a single trunk. As a result, there is no anterior communicating artery. This organization is similar to that seen in lower primates 1)

They are present in approximately 0.4-1% of the population 2)

Associations It is associated with numerous abnormalities, including 3)

dysgenesis of the corpus callosum

lobar holoprosencephaly 4)

septo-optic dysplasia

porencephalic cysts

arteriovenous malformations (AVM)

Berry aneurysms are often seen at the eventual bifurcation of the single vessel, due to either altered hemodynamics or congenitally abnormal wall, or both. The reported incidence varies widely, from 13 to 71% 5).

As there is frequent hypoplasia of the anterior communicating artery and supply of the medial surface of the hemispheres by contralateral ACA branches, confirmation of an azygos ACA can be difficult on angiography 6)

Cross compression views can be helpful.

1) , 6)
LeMay M, Gooding CA. The clinical significance of the azygos anterior cerebral artery (A.C.A.). Am J Roentgenol Radium Ther Nucl Med. 1966;98 (3): 602-10. Am J Roentgenol Radium Ther Nucl Med
2) , 3) , 5)
Huh JS, Park SK, Shin JJ et-al. Saccular aneurysm of the azygos anterior cerebral artery: three case reports. 2007;42 (4): 342-5. doi:10.3340/jkns.2007.42.4.342
Rossi A. Pediatric neuroradiology. Springer Verlag. (2005) ISBN:3540410775.
  • azygos_anterior_cerebral_artery.txt
  • Last modified: 2019/11/23 12:09
  • by administrador