Brain angiolipoma

Brain angiolipomas are extremely rare and almost all presented observations describe sellar tumors. On MRI study brain angiolipoma may be mistaken for pituitary adenoma or meningioma but fat saturation sequences and histological examination clear the diagnosis 1) 2) 3) 4).

In those rare cases when angiolipoma is found in cerebral hemispheres, it is important to establish the diagnosis before surgery to plan correct treatment and avoid complications, particularly profound bleeding 5).

Shekhtman et al. presented an untypical case of frontal lobe angiolipoma manifested with seizures and initially described as an arteriovenous malformation.

MRI with a fat-suppression sequence plays a key role in angiolipomas diagnostics. 6).

A patient with Klippel-Feil syndrome and multiple malformations, including tracheoesophageal fistula, bifid thumb and intracranial lipomas/angiolipomas, that have not been previously described in the syndrome, so it is considered an exceptional finding 7).

Wilkins PR, Hoddinott C, Hourihan MD, Davies KG, Sebugwawo S, Weeks RD: Intracranial angiolipoma. J Neurol Neurosurg Psychiatry 50:1057–1059, 1987
Pirotte B, Krischek B, Levivier M, Bolyn S, Brucher JM, Brotchi J: Diagnostic and microsurgical presentation of intracranial angiolipomas. Case report and review of the literature. J Neurosurg 88:129–132, 1998
Kolenc D, Zarković K, Jednacak H, Ozretić D, Habek M. Sellar angiolipomas: two case reports and a review of the literature. J Neurooncol. 2008 Aug;89(1):109-12.
Rotondo M., D’Avanzo R., Natale M., Oliva G., Scuotto A. Lateral sellar angiolipomas: a therapeutic challenge. Our experience on two cases and review of the literature. British Journal of Neurosurgery, June 2013; 27(3): 359–363.
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Shekhtman O, Gorozhanin V, Shishkina L. A Rare Case of Brain Angiolipoma Imitating Arteriovenous Malformation: Differential Diagnosis, Surgical Treatment, and Literature Review. World Neurosurg. 2018 Jun;114:264-268. doi: 10.1016/j.wneu.2018.03.167. Epub 2018 Mar 31. Review. PubMed PMID: 29614355.
Urdaneta Carruyo E, Rojas Zerpa G, Urdaneta Contreras A, Maldonado Alviarez M, Brito Rodríguez M. [Klippel-Feil syndrome with tracheoesophageal fistula, bifid thumb and cerebral angiolipoma.]. Arch Argent Pediatr. 2016 Dec 1;114(6):e398-e402. doi: 10.5546/aap.2016.e398. Spanish. PubMed PMID: 27869419.
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