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Carbonylation of cytoskeleton proteins could lead to depolymerization of their filaments and axonal injury, and proteasome suppression contributes to the accumulation of carbonylated proteins under oxidative conditions 1).

Zhang X, Li Z, Zhang Q, Chen L, Huang X, Zhang Y, Liu X, Liu W, Li W. Mechanisms Underlying H2O2-Evoked Carbonyl Modification of Cytoskeletal Protein and Axon Injury in PC-12 Cells. Cell Physiol Biochem. 2018 Jul 24;48(3):1088-1098. doi: 10.1159/000491975. [Epub ahead of print] PubMed PMID: 30041238.
carbonylation.txt · Last modified: 2018/07/25 13:51 by administrador