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Cardiac arrest

Yagi et al. monitored CBO in 20 patients with cardiac arrest by NIRS. On the arrival of patients at the emergency department, the attending physician immediately assessed whether the patient was eligible for this study after conventional advanced life support and, if eligible, measured CBO in the frontal lobe by NIRS. They found that in all patients, the cerebral blood flow waveform was in synchrony with the chest compressions. Moreover, the tissue oxygenation index increased following cardiopulmonary bypass (CPB) in patients undergoing CPB, including one patient in whom CBO was monitored using the NIRO-CCR1. In addition, although the NIRO-CCR1 could display the pulse rate (Tempo) in real-time, Tempo was not always detected, despite the detection of the cerebral blood flow waveform. This suggested that chest compressions may not have been effective, indicating that the NIRO-CCR1 also seems useful to assess the quality of CPR. This study suggests that the NIRO-CCR1 can measure CBO during CPR in patients with cardiac arrest as effectively as the NIRO-200NX; in addition, the new NIRO-CCR1 maybe even more useful, especially in prehospital fields (e.g. in an ambulance), since it is easy to carry 1).

Hayman et al. sought to review the role that cerebral edema plays in neurologic outcome following cardiac arrest, to understand whether cerebral edema might be an appropriate therapeutic target for neuroprotection in patients who survive cardiopulmonary resuscitation. Articles indexed in PubMed and written in English. Following cardiac arrest, cerebral edema is a cardinal feature of brain injury and is a powerful prognosticator of neurologic outcome. Like other conditions characterized by cerebral ischemia/reperfusion, neuroprotection after cardiac arrest has proven to be difficult to achieve. Neuroprotection after cardiac arrest generally has focused on protecting neurons, not the microvascular endothelium or blood-brain barrier. Limited preclinical data suggest that strategies to reduce cerebral edema may improve neurologic outcome. Ongoing research will be necessary to determine whether targeting cerebral edema will improve patient outcomes after cardiac arrest 2).

Yagi T, Kawamorita T, Kuronuma K, Tachibana E, Watanabe K, Chiba N, Ashida T, Atsumi W, Kunimoto S, Tani S, Matsumoto N, Okumura Y, Yoshino A, Sakatani K. Usefulness of a New Device to Monitor Cerebral Blood Oxygenation Using NIRS During Cardiopulmonary Resuscitation in Patients with Cardiac Arrest: A Pilot Study. Adv Exp Med Biol. 2020;1232:323-329. doi: 10.1007/978-3-030-34461-0_41. PubMed PMID: 31893427.
Hayman EG, Patel AP, Kimberly WT, Sheth KN, Simard JM. Cerebral Edema After Cardiopulmonary Resuscitation: A Therapeutic Target Following Cardiac Arrest? Neurocrit Care. 2017 Oct 27. doi: 10.1007/s12028-017-0474-8. [Epub ahead of print] PubMed PMID: 29080068.
cardiac_arrest.txt · Last modified: 2020/01/02 15:26 by administrador