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Cerebral hypoxia

Form of hypoxia (reduced supply of oxygen) specifically involving the brain

There are four categories of cerebral hypoxia; they are, in order of severity:

Diffuse cerebral hypoxia (DCH),

Focal cerebral ischemia, cerebral infarction, and global cerebral ischemia. Prolonged hypoxia induces neuronal cell death via apoptosis, resulting in a hypoxic brain injury.

The cranial cavity is a closed compartment and any breach to this confined space secondary to neurosurgery or trauma cause an imbalance between atmospheric pressure and intracranial pressure. As the altitude increases, the atmospheric pressure decreases and hypoxia with hypercarbia is a well-known fact. In children, there is an argument to suggest that hypoxia can contribute to mild increase in intracranial pressure during commercial flights 1).

Lo Presti A, Weil AG, Ragheb J. Flying with a shunt. J Neurosurg Pediatr. 2015;15(2):223-224.
cerebral_hypoxia.txt · Last modified: 2017/10/24 15:54 by administrador