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Cerebrospinal fluid fistula

A cerebrospinal fluid leak (CSFL) is a medical condition when the cerebrospinal fluid of a person leaks out of the dura mater.

There is a incomplete sealing of the dura mater and is a major complication of intradural procedures.


CSF leaks have been traditionally classified as traumatic or non-traumatic.

Non-traumatic CSF leak may be spontaneous in the absence of obvious cause, such as skull base abnormalities or bone erosion related to tumors or hydrocephalus 1) 2) 3).


This can be caused by several reasons, including spontaneous cerebrospinal fluid leak, post-surgical lumbar puncture (iatrogenic), physical trauma, etc.

It is a common complication of surgery involving the lumbar spine.

While high CSF pressure can make reclining unbearable, low CSF pressure due to a leak is often relieved somewhat by maintaining a supine position.

Posttraumatic cerebrospinal fluid leakage.

Spontaneous cerebrospinal fluid leak or nontraumatic.

see Postoperative cerebrospinal fluid fistula.


Cerebrospinal fluid otorrhea.

Cerebrospinal fluid rhinorrhea.


Pediatric cerebrospinal fluid leakage


Spinal cerebrospinal fluid leakage



Ommaya AK. Cerebrospinal Fluid Rhinorrhea. Neurology. 1964;14:106–113.
Clark D, Bullock P, Hui T, et al. Benign intracranial hypertension: a cause of CSF rhinorrhoea. J Neurol Neurosurg Psych. 1994;57:847–849.
Yang Z, Wang B, Wang C, et al. Primary spontaneous cerebrospinal fluid rhinorrhea: a symptom of idiopathic intracranial hypertension? J Neurosurg. 2011;115:165–170.
cerebrospinal_fluid_fistula.txt · Last modified: 2019/10/11 12:07 by administrador