cerebrospinal_fluid_rhinorrhea

Cerebrospinal fluid rhinorrhea

Common etiologies of CSF rhinorrhea include trauma, neoplasms, and prior surgery, while CSF otorrhea is usually associated with craniocerebral trauma, neurosurgical procedures, or other conditions; however, both conditions may occur spontaneously 1).

Nontraumatic cerebrospinal fluid fistula

Traumatic cerebrospinal fluid rhinorrhea

Sphenoid lateral recess Cerebrospinal fluid fistula

Through cribiform plate

Endoscopic CSF fistula closure is a safe and effective operation. All sites of leak can be accessed endoscopically 2).


Macroprolactinomas (MPRLs) may result in nonsurgical (spontaneous or dopamine agonist induced) cerebrospinal fluid (CSF) rhinorrhea; however, the incidence of and mechanisms underlying this phenomenon are poorly understood 3).


1)
May JS, Mikus JL, Matthews BL, Browne JD. Spontaneous cerebrospinal fluid otorrhea from defects of the temporal bone: a rare entity? Am J Otol. 1995 Nov;16(6):765-71. PMID: 8572139.
2)
Virk JS, Elmiyeh B, Saleh HA. Endoscopic management of cerebrospinal fluid rhinorrhea: the charing cross experience. J Neurol Surg B Skull Base. 2013 Apr;74(2):61-7. doi: 10.1055/s-0033-1333620. Epub 2013 Feb 13. PubMed PMID: 24436890; PubMed Central PMCID: PMC3699213.
3)
Suliman SG, Gurlek A, Byrne JV, Sullivan N, Thanabalasingham G, Cudlip S, Ansorge O, Wass JA. Nonsurgical cerebrospinal fluid rhinorrhea in invasive macroprolactinoma: incidence, radiological, and clinicopathological features. J Clin Endocrinol Metab. 2007 Oct;92(10):3829-35. Epub 2007 Jul 10. PubMed PMID: 17623759.
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  • Last modified: 2022/04/07 16:43
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