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Cervical degenerative disc disease outcome

Cervical degenerative disc disease may progress into compression of the spinal cord, or cervical spondylotic myelopathy (CSM), which can cause neurologic dysfunction.

Although recent work has focused on characterizing quantitative MRI markers that may predict outcome among patients with cervical degenerative conditions, little is known about their reliability. Measurement and reporting of these markers is time-consuming and non-standardized, thereby preventing their routine use in clinical care.

The good and very good reliability observed in measuring T2-weighted spinal cord signal change, level of worst compression, AP cord diameter, and kyphosis support the use of these markers in standardized reporting which could be incorporated into routine clinical use 1).

It is often accompanied by dizziness. It has been shown that the ingrowth of Bulbous corpuscles into diseased cervical discs may be related to cervicogenic dizziness.

Patients with CS appear to exhibit cortical thinning and atrophy with worsening neurological and pain symptoms in specific brain regions associated with sensorimotor and pain processing 2).


I appears to be safe to resume driving after discharge from hospital. However, patients scheduled to undergo anterior cervical discectomy and fusion should be informed about increased reduced driving reaction time (DRT) as compared to healthy individuals 3).

Many patients suffering from radiculopathy or myelopathy from cervical disc disease are limited in their ability to operate an automobile. Following anterior cervical spine surgery, most patients are able to return to comfortable driving at 6 weeks 4).

Grochmal JK, Lozen AM, Klein AP, Mark LP, Li J, Wang MC. Interobserver Reliability of MRI Predictors of Outcome in Cervical Spine Degenerative Conditions. World Neurosurg. 2018 Jun 15. pii: S1878-8750(18)31196-3. doi: 10.1016/j.wneu.2018.05.242. [Epub ahead of print] PubMed PMID: 29913296.
Woodworth DC, Holly LT, Mayer EA, Salamon N, Ellingson BM. Alterations in Cortical Thickness and Subcortical Volume are Associated With Neurological Symptoms and Neck Pain in Patients With Cervical Spondylosis. Neurosurgery. 2018 Mar 14. doi: 10.1093/neuros/nyy066. [Epub ahead of print] PubMed PMID: 29548020.
Lechner R, Thaler M, Krismer M, Haid C, Obernauer J, Obwegeser A. Driving reaction time before and after anterior cervical fusion for disc herniation: a preliminary study. Eur Spine J. 2013 Jul;22(7):1517-21. doi: 10.1007/s00586-013-2688-6. Epub 2013 Mar 10. PubMed PMID: 23474545; PubMed Central PMCID: PMC3698328.
Kelly MP, Mitchell MD, Hacker RJ, Riew KD, Sasso RC. Single-level degenerative cervical disc disease and driving disability: results from a prospective, randomized trial. Global Spine J. 2013 Dec;3(4):237-42. doi: 10.1055/s-0033-1354250. Epub 2013 Aug 28. PubMed PMID: 24436875; PubMed Central PMCID: PMC3854580.
cervical_degenerative_disc_disease_outcome.txt · Last modified: 2018/06/20 08:21 by administrador