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chromosome_1

Chromosome 1

The molecular hallmark feature of oligodendroglioma is codeletion of the short arm of chromosome 1 (1p) and the long arm of chromosome 19 (19q) 1), which is present in about 60–90% of histopathologically diagnosed oligodendroglioma 2).

1)
Jenkins RB, Blair H, Ballman KV, Giannini C, Arusell RM, Law M, Flynn H, Passe S, Felten S, Brown PD, Shaw EG, Buckner JC. A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma. Cancer Res. 2006 Oct 15;66(20):9852-61. PubMed PMID: 17047046.
2)
van den Bent MJ. Anaplastic oligodendroglioma and oligoastrocytoma. Neurol Clin. 2007 Nov;25(4):1089-109, ix-x. Review. PubMed PMID: 17964027.
chromosome_1.txt · Last modified: 2018/12/13 07:43 by administrador