cortical_thickness

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cortical_thickness [2021/03/07 21:17]
administrador
cortical_thickness [2021/03/07 21:19] (current)
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 Younger [[age]] at first [[exposure]] (AFE) to repetitive [[head]] [[impact]]s while playing [[American football]] increases the risk for later-life neuropsychological [[symptom]]s and brain alterations.  Younger [[age]] at first [[exposure]] (AFE) to repetitive [[head]] [[impact]]s while playing [[American football]] increases the risk for later-life neuropsychological [[symptom]]s and brain alterations. 
  
-Howeverit is not known whether AFE has associated with [[cortical thickness]] in [[American football]] players. Sixty-three former professional National Football League players (55.5 ± 7.7 years) with [[cognitive]], [[behavior]]al, and [[mood]] symptoms underwent neuroimaging and neuropsychological testing. First, the association between cortical thickness and AFE was tested. Second, the relationship between clusters of decreased cortical thickness and verbal and [[visual memory]], and composite measures of mood/behavior and attention/psychomotor speed were assessed. AFE was positively correlated with cortical thickness in the right superior [[frontal]] [[cortex]] (cluster-wise P-value [CWP] = 0.0006), the left [[parietal]] cortex (CWP = 0.0003), and the occipital cortices (right: CWP = 0.0023; left: CWP = 0.0008). A positive correlation was found between cortical thickness of the right superior frontal cortex and verbal memory (R = 0.333, P = 0.019), and the right occipital cortex and visual memory (R = 0.360, P = 0.012). In conclusion, the results suggest an association between younger AFE and decreased cortical thickness, which in turn is associated with worse neuropsychological performance. Furthermore, an association between younger AFE and signs of [[neurodegeneration]] later in life in symptomatic former American football players seems likely+Results suggest an association between younger AFE and decreased cortical thicknesswhich in turn is associated with worse neuropsychological performance. Furthermore, an association between younger AFE and signs of [[neurodegeneration]] later in life in symptomatic former American football players seems likely 
 +((Kaufmann D, Sollmann N, Kaufmann E, Veggeberg R, Tripodis Y, Wrobel PP, Kochsiek J, Martin BM, Lin AP, Coleman MJ, Alosco ML, Pasternak O, Bouix S, Stern RA, Shenton ME, Koerte IK. Age at First Exposure to Tackle Football is Associated with Cortical Thickness in Former Professional American Football Players. Cereb Cortex. 2021 Mar 2:bhab021. doi: 10.1093/cercor/bhab021. Epub ahead of print. PMID: 33676369.)). 
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 +Sixty-three former professional National Football League players (55.5 ± 7.7 years) with [[cognitive]], [[behavior]]al, and [[mood]] symptoms underwent neuroimaging and neuropsychological testing. First, the association between cortical thickness and AFE was tested. Second, the relationship between clusters of decreased cortical thickness and verbal and [[visual memory]], and composite measures of mood/behavior and attention/psychomotor speed were assessed. AFE was positively correlated with cortical thickness in the right superior [[frontal]] [[cortex]] (cluster-wise P-value [CWP] = 0.0006), the left [[parietal]] cortex (CWP = 0.0003), and the occipital cortices (right: CWP = 0.0023; left: CWP = 0.0008). A positive correlation was found between cortical thickness of the right superior frontal cortex and verbal memory (R = 0.333, P = 0.019), and the right occipital cortex and visual memory (R = 0.360, P = 0.012). In conclusion, the results suggest an association between younger AFE and decreased cortical thickness, which in turn is associated with worse neuropsychological performance. Furthermore, an association between younger AFE and signs of [[neurodegeneration]] later in life in symptomatic former American football players seems likely
 ((Kaufmann D, Sollmann N, Kaufmann E, Veggeberg R, Tripodis Y, Wrobel PP, Kochsiek J, Martin BM, Lin AP, Coleman MJ, Alosco ML, Pasternak O, Bouix S, Stern RA, Shenton ME, Koerte IK. Age at First Exposure to Tackle Football is Associated with Cortical Thickness in Former Professional American Football Players. Cereb Cortex. 2021 Mar 2:bhab021. doi: 10.1093/cercor/bhab021. Epub ahead of print. PMID: 33676369.)). ((Kaufmann D, Sollmann N, Kaufmann E, Veggeberg R, Tripodis Y, Wrobel PP, Kochsiek J, Martin BM, Lin AP, Coleman MJ, Alosco ML, Pasternak O, Bouix S, Stern RA, Shenton ME, Koerte IK. Age at First Exposure to Tackle Football is Associated with Cortical Thickness in Former Professional American Football Players. Cereb Cortex. 2021 Mar 2:bhab021. doi: 10.1093/cercor/bhab021. Epub ahead of print. PMID: 33676369.)).
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  • Last modified: 2021/03/07 21:19
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