see Oculomotor nerve palsy

see Trochlear nerve palsy

Cranial nerve palsy (CNP) secondary to cerebrospinal fluid diversion is less familiar to us as a result of its rarity in incidence and insidiousness in presentation.

From June 2012 to February 2015, 5 of 347 consecutive patients with CNPs secondary to different CSF diversion procedures were treated at The First Hospital of Jilin University, Changchun, Jilin, China.

A systematic PubMed search of published studies written in English for patients developing CNPs after CSF diversion procedures from January 1950 to June 2015 was conducted.

Overall, 29 studies and 5 patients of the current series totaling 53 CNPs met the inclusion criteria. CN II, III, IV, V, VI, VII and VIII were got involved in 2 (3.8%), 2 (3.8%), 5 (9.4%), 1 (1.9%), 44 (83.0%), 4 (7.5%) and 1 (1.9%) patients respectively. Thirty-eight patients (71.7%) developed CNPs following inadvertent lumbar puncture, 8 (15.1%) following lumbar drainage, and 7 (13.2%) following ventriculoperitoneal shunt. Forty-eight (90.6%) patients got resolved completely.

The proposed mechanism of CNP after CSF diversion procedure is cerebrospinal fluid hypovolemia and subsequent downward displacement of the brain and traction and distortion of the vascular and peripheral neural structures. As a result of its distinct anatomic characteristics rather than long intracranial course, CN VI is most commonly affected. With early recognition and timely conservative management, most patients could get favorable recovery 1)

Li G, Zhu X, Zhang Y, Zhao J, Han Z, Hou K. Cranial nerve palsy secondary to cerebrospinal fluid diversion. Clin Neurol Neurosurg. 2016 Apr;143:19-26. doi: 10.1016/j.clineuro.2016.02.010. Epub 2016 Feb 9. PubMed PMID: 26882270.
  • cranial_nerve_palsy.txt
  • Last modified: 2016/11/10 16:44
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