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craniopharyngioma [2022/05/16 12:34] – [Differential diagnosis] administrador | craniopharyngioma [2022/05/16 12:38] (current) – administrador | ||
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===== Epidemiology ===== | ===== Epidemiology ===== | ||
- | Incidence of 0.13 cases per 100,000 people every year. They represent approximately 2%–5% of all primary brain tumors and have a bimodal presentation in children aged 5–14 and adults aged 55–65 years | + | [[Craniopharyngioma epidemiology]]. |
- | The incidence of craniopharyngioma in the United States was estimated from two population-based cancer registries that include brain tumors of benign and borderline malignancy: the Central Brain Tumor Registry of the United States (CBTRUS) and the Los Angeles county Cancer Surveillance Program. Information on additional pediatric tumors was available from the Greater Delaware Valley Pediatric Tumor Registry (GDVPTR). The overall incidence of craniopharyngioma was 0.13 per 100,000 person years and did not vary by gender or race. A bimodal distribution by age was noted with peak incidence rates in children (aged 5-14 years) and among older adults (aged 65-74 years in CBTRUS and 50-74 years in Los Angeles county). Survival information was available from GDVPTR and the National Cancer Data Base (NCDB), a hospital-based reporting system. In the NCDB, the 5-year survival rate was 80% and decreased with older age at diagnosis. Survival is higher among children and has improved in recent years. | ||
- | Craniopharyngioma is a rare brain tumor of uncertain behavior that occurs at a rate of 1.3 per million person years. Approximately 338 cases of this disease are expected to occur annually in the United States, with 96 occurring in children from 0 to 14 years of age | ||
- | ((Bunin GR, Surawicz TS, Witman PA, Preston-Martin S, Davis F, Bruner JM. The | ||
- | descriptive epidemiology of craniopharyngioma. J Neurosurg. 1998 | ||
- | Oct; | ||
- | )). | ||
- | ---- | ||
- | The Childhood Cancer Registry of Piedmont, Italy, estimates an incidence of 1.4 cases per million children per year. Similar data are provided by other registries in Western countries, while higher rates have been observed in Asia and Africa. There are no known specific environmental risk factors for craniopharyngioma, | ||
- | ((Haupt R, Magnani C, Pavanello M, Caruso S, Dama E, Garrè ML. Epidemiological | ||
- | aspects of craniopharyngioma. J Pediatr Endocrinol Metab. 2006 Apr;19 Suppl | ||
- | 1:289-93. Review. PubMed PMID: 16700303. | ||
- | )). | ||
- | ---- | ||
- | Zacharia et al., used the surveillance, | ||
- | ((Zacharia BE, Bruce SS, Goldstein H, Malone HR, Neugut AI, Bruce JN. Incidence, | ||
- | treatment and survival of patients with craniopharyngioma in the surveillance, | ||
- | epidemiology and end results program. Neuro Oncol. 2012 Aug; | ||
- | 10.1093/ | ||
- | )). | ||
====Origin==== | ====Origin==== | ||
Its relation to Rathke' | Its relation to Rathke' | ||
It grows close to the [[optic nerve]], [[hypothalamus]] and [[pituitary gland]]. | It grows close to the [[optic nerve]], [[hypothalamus]] and [[pituitary gland]]. | ||
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===== Classification ===== | ===== Classification ===== |