Cushing's disease

Cushing's name is commonly associated with his most famous discovery, Cushing's disease. In 1912 he reported in a study an endocrinological syndrome caused by a malfunction of the pituitary gland which he termed “polyglandular syndrome.” He published his findings in 1932 as “The Basophil Adenomas of the Pituitary Body and Their Clinical Manifestations: pituitary Basophilism”.

Cushing's disease (also known as Cushing disease, tertiary or secondary hypercortisolism, tertiary or secondary hypercorticism, Itsenko-Cushing disease) is a cause of Cushing's syndrome characterised by increased secretion of adrenocorticotropic hormone (ACTH) from Pituitary Corticotroph Adenoma (the anterior pituitary secondary hypercortisolism), leading to excess glucocorticoid and hypercortisolism.

see Pituitary Corticotroph Adenoma.

  • cushing_s_disease.txt
  • Last modified: 2021/04/18 08:59
  • by administrador