Dermoid cysts (DCs) are unusual benign congenital intracranial tumors that typically arise in the midline and form as a result of abnormal sequestration of ectodermal cells during neural tube formation.
These uni or multilocular cystic tumours lined by squamous epithelium containing skin appendages (hair follicles, sweat glands, sebaceous glands) are congenital in origin.
They are considered benign, and in all reported cases the cysts were well encapsulated on surgical removal. However, a case of squamous cell carcinoma dedifferentiation has been reported, and a few cases of rupture of the cyst leading to aseptic meningitis have been described 2) 3).
Dermoids are not unique to a single anatomic location but are often isolated to the skin and subcutaneous tissue.
They may occur intracranially or intra-abdominally, oftentimes associated with the ovary.
The intracranial lesions are commonly located in the posterior fossa.
see Cranial dermoid cyst.
In contrast to more common nasal and cervical lesions, the frontotemporal pit is a rarely encountered lesion that is often associated with a dermoid and may track intracranially. Due to delays in diagnosis, the propensity to spread intracranially, and the risk of infection, awareness of these lesions and appropriate diagnosis and management are important. Bliss et al., present 2 cases of frontotemporal pits from a single institution. Epidemiology, presentation, and management recommendations are discussed 4).