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Dopamine overdose hypothesis

Posits that the excess of exogenous dopamine in the frontal cortical regions can impair cognition.

Findings demonstrate dopamine-related dissociation in brain activation between cortical and subcortical regions, and provide novel support for the dopamine overdose hypothesis 1).

Kim J, Zhang K, Cai W, YorkWilliams S, I Ua Cruadhlaoich MA, Llanes S, Menon V, Poston KL. Dopamine-Related Dissociation of Cortical and Subcortical Brain Activations in Cognitively Unimpaired Parkinson's Disease Patients OFF and ON Medications. Neuropsychologia. 2018 Jul 21. pii: S0028-3932(18)30377-4. doi: 10.1016/j.neuropsychologia.2018.07.024. [Epub ahead of print] PubMed PMID: 30040957.
dopamine_overdose_hypothesis.txt · Last modified: 2018/07/25 13:57 by administrador