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Electromagnetic field

Human exposures to electromagnetic fields are ubiquitous in modern society, and the number of new applications is constantly increasing.

Introduction of new technologies, such as mobile telephone, has raised public concern about potential health effects from exposures to electromagnetic fields at levels far below current guidelines 1) 2).

Mindermann and Mendelowitsch published a case report, where a high grade glioma was observed in a patient who had previously been treated with deep brain stimulation 3).

The authors speculate that electric fields associated with the treatment could have caused the tumour. The authors also mention a case report describing the development of glioblastoma in two patients who had cochlear implants, where it was suggested that the tumours might be attributed to the electromagnetic fields from the implants 4).

Both of these are interesting observations, although alternative explanations for the ccurrence of the tumours in these patients may be at least as, or even more, plausible. It should be noted that the electromagnetic field exposures from these two applications are very different, with different properties; DBS is used to achieve stimulation of specific areas of the brain through electric impulses. Thus, with DBS, a biological effect is the goal of the treatment, whereas cochlear implants use radiofrequency fields to transfer sound over a very short distance, at field levels that, according to current knowledge, are too low to cause biological effects outside the normal physiological variation. To properly test the hypothesis that the electromagnetic fields from DBS or cochlear implants causes glioma, systematic epidemiological studies need to be conducted, where sizeable cohorts of patients who have undergone DBS or had cochlear implants are observed with regard to the occurrence of glioma over a sufficiently long time period, and where the observed glioma incidence is compared to the incidence in the general population of comparable age and sex distribution. As confounding from the surgical procedures necessary to apply the devices cannot be excluded, additional support from epidemiological studies of other electromagnetic field exposure sources would also be needed, as well as support from experimental studies. Currently, the evidence in support of the hypothesis that radiofrequency fields from mobile phone use increase the risk of glioma is very limited 5) 6).

Increased risks have been reported by a few case–control studies that have assessed exposure through retrospectively collected self-reported information about mobile phone use, which is prone to recall bias, and reported risk increases have often been implausible in the light of the stable glioma incidence trends worldwide since the introduction of handheld mobile phones 7) 8).

In addition, cohort studies that have collected exposure information independently of the disease have found no evidence of increased glioma risks 9) 10).

1) , 5) , 9)
AGNIR (2012) Health effects from radiofrequency electromagnetic fields. Report from the Independent Advisory Group on NonIonising Radiation. Documents of the Health Protection Agency, Radiation, Chemical and Environmental Hazards. RCE 20, Health Protection Agency, London
2) , 6) , 10)
SCENIHR (2015) Scientific Committee on emerging and newly identified health risks: potential health effects of exposure to electromagnetic fields (EMF). committees/emerging/docs/scenihr_o_041.pdf. Accessed 15 Aug 2015
Mindermann T, Mendelowitsch A. Deep brain stimulation and development of a high-grade glioma: incidental or causal association? Acta Neurochir (Wien). 2016 May;158(5):915-7. doi: 10.1007/s00701-016-2773-9. Epub 2016 Mar 18. PubMed PMID: 26993141.
Kalakoti P, Murray R, Pettersson-Segerlind J, Smeds H, Nanda A (2016) Cochlear implants in the etio-pathogenesis of glioblastoma— an interesting observation or an independent finding? Acta Neurochir (Wein). doi:10.1007/s00701-016-2718-3
Deltour I, Auvinen A, Feychting M, Johansen C, Klaeboe L, Sankila R, Schuz J (2012) Mobile phone use and incidence of glioma in the Nordic countries 1979–2008: consistency check. Epidemiology 23: 301–307. doi:10.1097/EDE.0b013e3182448295
Little MP, Rajaraman P, Curtis RE, Devesa SS, Inskip PD, Check DP, Linet MS (2012) Mobile phone use and glioma risk: comparison of epidemiological study results with incidence trends in the United States. BMJ 344:e1147. doi:10.1136/bmj.e1147
electromagnetic_field.txt · Last modified: 2016/05/05 16:01 (external edit)