Osteoporosis may predispose to vertebral compression fractures which occur in 30–50% of patients on prolonged glucocorticoids. Steroid-induced bone loss may be reversed with cyclical administration of etidronate 1) in 4 cycles of 400 mg/d ✖ 14 days followed by 76 days of oral calcium supplements of 500 mg/d (not proven to a reduced rate of vertebral fractures).

Struys A, Snelder AA, Mulder H. Cyclical Etidronate Reverses Bone Loss of the Spine and Proximal Femur in Patients With Established Corticosteroid- Induced Osteoporosis. Am J Med. 1995; 99:235–242
  • etidronic_acid.txt
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