The lateral aperture is a paired structure.
It is an opening in each lateral extremity of the lateral recess of the fourth ventricle of the human brain, which also has a single median aperture. The two lateral apertures provide a conduit for cerebrospinal fluid to flow from the brain's ventricular system into the subarachnoid space; specifically into the cerebellopontine angle. The structure is also called the lateral aperture of the fourth ventricle or the foramen of Luschka after anatomist Hubert von Luschka.
Lesions lateral to the lower brainstem in an area extending from the foraminae of Luschka to the foramen magnum are rare and include different pathologies. There is no consensus on an ideal surgical approach.