Gemelli University Hospital

The Gemelli University Hospital (Italian: Fondazione Policlinico Universitario Agostino Gemelli) is a large general hospital in Rome, Italy. With 1575 beds, it is the second-largest hospital in Italy, the largest hospital in Rome and one of the largest private hospitals in Europe.

It serves as the teaching hospital for the medical school of the Università Cattolica del Sacro Cuore (the largest privately owned university in Italy, founded in 1921 in Milan), and owes its name to the university founder, the Franciscan friar, physician and psychologist Agostino Gemelli. The hospital provides free medical assistance as part of the Italian national health system as well as paid-for private assistance in dedicated hotel-style wards.

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29: Gielen GH, Baugh JN, van Vuurden DG, Veldhuijzen van Zanten SEM, Hargrave D, Massimino M, Biassoni V, Morales la Madrid A, Karremann M, Wiese M, Thomale U, Janssens GO, von Bueren AO, Perwein T, Nussbaumer G, Hoving EW, Niehusmann P, Gessi M, Kwiecien R, Bailey S, Pietsch T, Andreiuolo F, Kramm CM. Pediatric high-grade gliomas and the WHO CNS Tumor Classification-Perspectives of pediatric neuro-oncologists and neuropathologists in light of recent updates. Neurooncol Adv. 2022 May 20;4(1):vdac077. doi: 10.1093/noajnl/vdac077. PMID: 35733513; PMCID: PMC9209749.

30: Catanzaro G, Besharat ZM, Carai A, Jäger N, Splendiani E, Colin C, Po A, Chiacchiarini M, Citarella A, Gianno F, Cacchione A, Miele E, Diomedi Camassei F, Gessi M, Massimi L, Locatelli F, Jones DTW, Figarella-Branger D, Pfister SM, Mastronuzzi A, Giangaspero F, Ferretti E. MiR-1248: a new prognostic biomarker able to identify supratentorial hemispheric pediatric low-grade gliomas patients associated with progression. Biomark Res. 2022 Jun 17;10(1):44. doi: 10.1186/s40364-022-00389-x. PMID: 35715818; PMCID: PMC9205050.

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38: Gerardi RM, Giammalva GR, Basile L, Gulì C, Pino MA, Messina D, Umana GE, Graziano F, di Bonaventura R, Sturiale CL, Visocchi M, Iacopino DG, Maugeri R. White Cord Syndrome After Cervical or Thoracic Spinal Cord Decompression. Hemodynamic Complication or Mechanical Damage? An Underestimated Nosographic Entity. World Neurosurg. 2022 Aug;164:243-250. doi: 10.1016/j.wneu.2022.05.012. Epub 2022 May 16. PMID: 35589039.

39: Vasavda C, Semenza ER, Liew J, Kothari R, Dhindsa RS, Shanmukha S, Lin A, Tokhunts R, Ricco C, Snowman AM, Albacarys L, Pastore F, Ripoli C, Grassi C, Barone E, Kornberg MD, Dong X, Paul BD, Snyder SH. Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling. Sci Signal. 2022 May 10;15(733):eabh3066. doi: 10.1126/scisignal.abh3066. Epub 2022 May 10. PMID: 35536885; PMCID: PMC9281001.

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41: Costanzo R, Brunasso L, Paolini F, Benigno UE, Porzio M, Giammalva GR, Gerardi RM, Umana GE, di Bonaventura R, Sturiale CL, Visocchi M, Iacopino DG, Maugeri R. Spinal Tractography as a Potential Prognostic Tool in Spinal Cord Injury: A Systematic Review. World Neurosurg. 2022 Aug;164:25-32. doi: 10.1016/j.wneu.2022.04.103. Epub 2022 Apr 29. PMID: 35500874.

42: Mulroy E, Macerollo A, Scotton S, Cociasu I, Di Lazzaro G, Bashir S, Doherty J, Hamid S, Mooney N, Batla A, Morgante F, Bhatia KP. Ethnic Differences in Dystonia Prevalence and Phenotype. Mov Disord. 2022 Jun;37(6):1323-1325. doi: 10.1002/mds.29034. Epub 2022 May 2. PMID: 35500158.

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44: Brunasso L, Ferini G, Bonosi L, Costanzo R, Musso S, Benigno UE, Gerardi RM, Giammalva GR, Paolini F, Umana GE, Graziano F, Scalia G, Sturiale CL, Di Bonaventura R, Iacopino DG, Maugeri R. A Spotlight on the Role of Radiomics and Machine-Learning Applications in the Management of Intracranial Meningiomas: A New Perspective in Neuro-Oncology: A Review. Life (Basel). 2022 Apr 14;12(4):586. doi: 10.3390/life12040586. PMID: 35455077; PMCID: PMC9026541.

45: Giammalva GR, Ferini G, Torregrossa F, Brunasso L, Musso S, Benigno UE, Gerardi RM, Bonosi L, Costanzo R, Paolini F, Palmisciano P, Umana GE, Di Bonaventura R, Sturiale CL, Iacopino DG, Maugeri R. The Palliative Care in the Metastatic Spinal Tumors. A Systematic Review on the Radiotherapy and Surgical Perspective. Life (Basel). 2022 Apr 12;12(4):571. doi: 10.3390/life12040571. PMID: 35455062; PMCID: PMC9032747.

46: Paolini F, Ferini G, Bonosi L, Costanzo R, Brunasso L, Benigno UE, Porzio M, Gerardi RM, Giammalva GR, Umana GE, Graziano F, Scalia G, Sturiale CL, Di Bonaventura R, Iacopino DG, Maugeri R. Spinal Cord Stimulation to Treat Unresponsive Cancer Pain: A Possible Solution in Palliative Oncological Therapy. Life (Basel). 2022 Apr 7;12(4):554. doi: 10.3390/life12040554. PMID: 35455045; PMCID: PMC9025741.

47: Costanzo R, Ferini G, Brunasso L, Bonosi L, Porzio M, Benigno UE, Musso S, Gerardi RM, Giammalva GR, Paolini F, Palmisciano P, Umana GE, Sturiale CL, Di Bonaventura R, Iacopino DG, Maugeri R. The Role of 3D-Printed Custom-Made Vertebral Body Implants in the Treatment of Spinal Tumors: A Systematic Review. Life (Basel). 2022 Mar 28;12(4):489. doi: 10.3390/life12040489. PMID: 35454979; PMCID: PMC9030237.

48: Buwenge M, Arcelli A, Cellini F, Deodato F, Macchia G, Cilla S, Galietta E, Strigari L, Malizia C, Cammelli S, Morganti AG. Pain Relief after Stereotactic Radiotherapy of Pancreatic Adenocarcinoma: An Updated Systematic Review. Curr Oncol. 2022 Apr 11;29(4):2616-2629. doi: 10.3390/curroncol29040214. PMID: 35448188; PMCID: PMC9032429.

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50: Zaed I, Safa A, Spennato P, Mottolese C, Chibbaro S, Cannizzaro D, Faggin R, Frassanito P, Maduri R, Messerer M, Servadei F. A Multicentric European Clinical Study on Custom-Made Porous Hydroxyapatite Cranioplasty in a Pediatric Population. Front Surg. 2022 Mar 23;9:848620. doi: 10.3389/fsurg.2022.848620. PMID: 35402489; PMCID: PMC8983879.

51: Lancellotta V, Fanetti G, Monari F, Mangoni M, Mazzarotto R, Tagliaferri L, Gobitti C, Lodi Rizzini E, Talomo S, Turturici I, Paiar F, Corvò R, Jereczek- Fossa BA, Donato V, Vianello F. Stereotactic radiotherapy (SRT) for differentiated thyroid cancer (DTC) oligometastases: an AIRO (Italian association of radiotherapy and clinical oncology) systematic review. Radiol Med. 2022 Jun;127(6):681-689. doi: 10.1007/s11547-022-01489-2. Epub 2022 Apr 8. PMID: 35394605.

52: Galieri G, Mazzucchi E, Pignotti F, Rinaldi P, De Santis V, La Rocca G, Sabatino G. Lumbo-sacral pedicular aplasia diagnosis and treatment: a systematic literature review and case report. Br J Neurosurg. 2022 Apr 8:1-7. doi: 10.1080/02688697.2022.2057431. Epub ahead of print. PMID: 35393903.

53: Trevisi G, Scerrati A, Rustemi O, Ricciardi L, Raneri F, Tomatis A, Piazza A, Auricchio AM, Stifano V, Dughiero M, DE Bonis P, Mangiola A, Sturiale CL. The role of the craniotomy size in the surgical evacuation of acute subdural hematomas in elderly patients: a retrospective multicentric study. J Neurosurg Sci. 2022 Apr 5. doi: 10.23736/S0390-5616.22.05648-X. Epub ahead of print. PMID: 35380204.

54: Stumpo V, Latour K, Trevisi G, Valente I, D'Arrigo S, Olivi A, Sturiale CL. Comparison between rupture/growth risk scores and treatment recommendation scores application to aneurysmal subarachnoid hemorrhage patients: A multicenter cross-reliability assessment study. J Clin Neurosci. 2022 May;99:359-366. doi: 10.1016/j.jocn.2022.03.034. Epub 2022 Mar 29. PMID: 35364438.

55: Kroese TE, van Laarhoven HWM, Nilsson M, Lordick F, Guckenberger M, Ruurda JP, D'Ugo D, Haustermans K, van Cutsem E, van Hillegersberg R, van Rossum PSN. Definition of oligometastatic esophagogastric cancer and impact of local oligometastasis-directed treatment: A systematic review and meta-analysis. Eur J Cancer. 2022 May;166:254-269. doi: 10.1016/j.ejca.2022.02.018. Epub 2022 Mar 24. PMID: 35339868.

56: Bonosi L, Ferini G, Giammalva GR, Benigno UE, Porzio M, Giovannini EA, Musso S, Gerardi RM, Brunasso L, Costanzo R, Paolini F, Graziano F, Scalia G, Umana GE, Di Bonaventura R, Sturiale CL, Iacopino DG, Maugeri R. Liquid Biopsy in Diagnosis and Prognosis of High-Grade Gliomas; State-of-the-Art and Literature Review. Life (Basel). 2022 Mar 11;12(3):407. doi: 10.3390/life12030407. PMID: 35330158; PMCID: PMC8950809.

57: De Martino L, Picariello S, Triarico S, Improda N, Spennato P, Capozza MA, Grandone A, Santoro C, Cioffi D, Attinà G, Cinalli G, Ruggiero A, Quaglietta L. Diencephalic Syndrome Due to Optic Pathway Gliomas in Pediatric Patients: An Italian Multicenter Study. Diagnostics (Basel). 2022 Mar 9;12(3):664. doi: 10.3390/diagnostics12030664. PMID: 35328218; PMCID: PMC8947184.

58: Deodato F, Pezzulla D, Cilla S, Ferro M, Buwenge M, Morganti AG, Macchia G. Reply to “Letter to the editor regarding 'Stereotactic radiosurgery for bone metastases in oligometastatic prostate cancer patients: DESTROY-2 clinical trial subanalysis'”. Clin Transl Oncol. 2022 Jun;24(6):1217-1218. doi: 10.1007/s12094-022-02813-y. Epub 2022 Mar 19. PMID: 35305244.

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60: Zoli M, Bongetta D, Raffa G, Somma T, Zoia C, Della Pepa GM. Young Neurosurgeons and Technology: Survey of Young Neurosurgeons Section of Italian Society of Neurosurgery (Società Italiana di Neurochirurgia, SINch). World Neurosurg. 2022 Jun;162:e436-e456. doi: 10.1016/j.wneu.2022.03.022. Epub 2022 Mar 11. PMID: 35283359.

61: Ricciardi L, Sturiale CL, Scerrati A, Stifano V, Somma T, Ius T, Trungu S, Acqui M, Raco A, Miscusi M, Della Pepa GM. 5-Aminolevulinic Acid False-Positive Rates in Newly Diagnosed and Recurrent Glioblastoma: Do Pseudoprogression and Radionecrosis Play a Role? A Meta-Analysis. Front Oncol. 2022 Feb 17;12:848036. doi: 10.3389/fonc.2022.848036. PMID: 35252015; PMCID: PMC8891510.

62: Moresi F, Rossetti DV, Vincenzoni F, Simboli GA, La Rocca G, Olivi A, Urbani A, Sabatino G, Desiderio C. Investigating Glioblastoma Multiforme Sub-Proteomes: A Computational Study of CUSA Fluid Proteomic Data. Int J Mol Sci. 2022 Feb 12;23(4):2058. doi: 10.3390/ijms23042058. PMID: 35216175; PMCID: PMC8879425.

63: Macchia G, Nardangeli A, Laliscia C, Fodor A, Draghini L, Gentile PC, D'Agostino GR, Balcet V, Bonome P, Ferioli M, Autorino R, Vicenzi L, Raguso A, Borghesi S, Ippolito E, Di Cataldo V, Cilla S, Perrucci E, Campitelli M, Gambacorta MA, Deodato F, Scambia G, Ferrandina G. Stereotactic body radiotherapy in oligometastatic cervical cancer (MITO-RT2/RAD study): a collaboration of MITO, AIRO GYN, and MaNGO groups. Int J Gynecol Cancer. 2022 Jun 6;32(6):732-739. doi: 10.1136/ijgc-2021-003237. PMID: 35193941.

64: Vergari A, Frassanito L, DI Muro M, Nestorini R, Chierichini A, Rossi M, DI Stasio E. Bilateral lumbar ultrasound-guided erector spinae plane block versus local anesthetic infiltration for perioperative analgesia in lumbar spine surgery: a randomized controlled trial. Minerva Anestesiol. 2022 Jun;88(6):465-471. doi: 10.23736/S0375-9393.22.15950-X. Epub 2022 Feb 22. PMID: 35191639.

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66: Giammalva GR, Ferini G, Musso S, Salvaggio G, Pino MA, Gerardi RM, Brunasso L, Costanzo R, Paolini F, Di Bonaventura R, Umana GE, Graziano F, Palmisciano P, Scalia G, Tumbiolo S, Midiri M, Iacopino DG, Maugeri R. Intraoperative Ultrasound: Emerging Technology and Novel Applications in Brain Tumor Surgery. Front Oncol. 2022 Feb 1;12:818446. doi: 10.3389/fonc.2022.818446. PMID: 35178348; PMCID: PMC8844995.

67: Kroese TE, van Hillegersberg R, Schoppmann S, Deseyne PRAJ, Nafteux P, Obermannova R, Nordsmark M, Pfeiffer P, Hawkins MA, Smyth E, Markar S, Hanna GB, Cheong E, Chaudry A, Elme A, Adenis A, Piessen G, Gani C, Bruns CJ, Moehler M, Liakakos T, Reynolds J, Morganti A, Rosati R, Castoro C, D'Ugo D, Roviello F, Bencivenga M, de Manzoni G, Jeene P, van Sandick JW, Muijs C, Slingerland M, Nieuwenhuijzen G, Wijnhoven B, Beerepoot LV, Kolodziejczyk P, Polkowski WP, Alsina M, Pera M, Kanonnikoff TF, Nilsson M, Guckenberger M, Monig S, Wagner D, Wyrwicz L, Berbee M, Gockel I, Lordick F, Griffiths EA, Verheij M, van Rossum PSN, van Laarhoven HWM; OMEC working group. Definitions and treatment of oligometastatic oesophagogastric cancer according to multidisciplinary tumour boards in Europe. Eur J Cancer. 2022 Mar;164:18-29. doi: 10.1016/j.ejca.2021.11.032. Epub 2022 Feb 5. PMID: 35134666.

68: Giammalva GR, Costanzo R, Paolini F, Benigno UE, Porzio M, Brunasso L, Basile L, Gulì C, Pino MA, Gerardi RM, Messina D, Umana GE, Palmisciano P, Scalia G, Graziano F, Visocchi M, Iacopino DG, Maugeri R. Management of Spinal Bone Metastases With Radiofrequency Ablation, Vertebral Reinforcement and Transpedicular Fixation: A Retrospective Single-Center Case Series. Front Oncol. 2022 Jan 21;11:818760. doi: 10.3389/fonc.2021.818760. PMID: 35127531; PMCID: PMC8814334.

69: Menna G, Manini I, Cesselli D, Skrap M, Olivi A, Ius T, Della Pepa GM. Immunoregulatory effects of glioma-associated stem cells on the glioblastoma peritumoral microenvironment: a differential PD-L1 expression from core to periphery? Neurosurg Focus. 2022 Feb;52(2):E4. doi: 10.3171/2021.11.FOCUS21589. PMID: 35104793.

70: Mancini A, Arosio M, Kreitschmann-Andermahr I, Persani L. Editorial: New Insights and Controversies in Diagnosis and Treatment of Adult Growth Hormone Deficiency. Front Endocrinol (Lausanne). 2022 Jan 10;12:819527. doi: 10.3389/fendo.2021.819527. PMID: 35082761; PMCID: PMC8785338.

71: Siller S, Skrap B, Grabein B, Trabold R, Zausinger S, Tonn JC. Routine intraoperative microbiological smear testing in patients with reoperation after elective degenerative non-instrumented spine surgery-useful or negligible adjunct. Acta Neurochir (Wien). 2022 Mar;164(3):891-901. doi: 10.1007/s00701-022-05132-x. Epub 2022 Jan 26. PMID: 35080653.

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73: Astrea G, Morrow JM, Manzur A, Gunny R, Battini R, Mercuri E, Reilly MM, Muntoni F, Yousry TA. Muscle “islands”: An MRI signature distinguishing neurogenic from myopathic causes of early onset distal weakness. Neuromuscul Disord. 2022 Feb;32(2):142-149. doi: 10.1016/j.nmd.2021.11.003. Epub 2021 Nov 18. PMID: 35033413.

74: Scerrati A, Trevisi G, Sturiale CL, Salomi F, De Bonis P, Saletti A, Mangiola A, Tomatis A, Di Egidio V, Vigo V, Pedicelli A, Valente I, Rustemi O, Beggio G, Iannucci G, Milonia L, Ricciardi L, Cervo A, Pero G, Piano M. Radiological outcomes for endovascular treatment of posterior communicating artery aneurysms: a retrospective multicenter study of the occlusion rate. J Integr Neurosci. 2021 Dec 30;20(4):919-931. doi: 10.31083/j.jin2004093. PMID: 34997715.

75: Deodato F, Pezzulla D, Cilla S, Ferro M, Romano C, Bonome P, Buwenge M, Zamagni A, Strigari L, Valentini V, Morganti AG, Macchia G. Stereotactic radiosurgery for bone metastases in oligometastatic prostate cancer patients: DESTROY-2 clinical trial subanalysis. Clin Transl Oncol. 2022 Jun;24(6):1177-1183. doi: 10.1007/s12094-021-02764-w. Epub 2022 Jan 4. PMID: 34984604.

76: Minniti G, Lanzetta G, Capone L, Giraffa M, Russo I, Cicone F, Bozzao A, Alongi F, Nicosia L, Fineschi G, Marchetti L, Tufo T, Bianciardi F, Esposito V, Gentile P, Paolini S. Leptomeningeal disease and brain control after postoperative stereotactic radiosurgery with or without immunotherapy for resected brain metastases. J Immunother Cancer. 2021 Dec;9(12):e003730. doi: 10.1136/jitc-2021-003730. PMID: 34949695; PMCID: PMC8705219.

77: Mercuri E, Deconinck N, Mazzone ES, Nascimento A, Oskoui M, Saito K, Vuillerot C, Baranello G, Boespflug-Tanguy O, Goemans N, Kirschner J, Kostera- Pruszczyk A, Servais L, Gerber M, Gorni K, Khwaja O, Kletzl H, Scalco RS, Staunton H, Yeung WY, Martin C, Fontoura P, Day JW; SUNFISH Study Group. Safety and efficacy of once-daily risdiplam in type 2 and non-ambulant type 3 spinal muscular atrophy (SUNFISH part 2): a phase 3, double-blind, randomised, placebo- controlled trial. Lancet Neurol. 2022 Jan;21(1):42-52. doi: 10.1016/S1474-4422(21)00367-7. Erratum in: Lancet Neurol. 2022 Feb;21(2):e2. Erratum in: Lancet Neurol. 2022 Mar;21(3):e3. Erratum in: Lancet Neurol. 2022 May;21(5):e5. PMID: 34942136.

78: Umana GE, Visocchi M, Roca E, Passanisi M, Fricia M, Tranchina MG, Tomasi SO, Nicoletti GF, Cicero S, Scalia G. Thoracic Spinal Angiolipomas: A Systematic Review. J Neurol Surg A Cent Eur Neurosurg. 2022 Mar;83(2):161-172. doi: 10.1055/s-0041-1739217. Epub 2021 Dec 20. PMID: 34929751.

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149: Piano C, Bove F, Tufo T, Imbimbo I, Genovese D, Stefani A, Marano M, Peppe A, Brusa L, Cerroni R, Motolese F, Di Stasio E, Mazza M, Daniele A, Olivi A, Calabresi P, Bentivoglio AR; Lazio DBS Study Group. Effects of COVID-19 Lockdown on Movement Disorders Patients With Deep Brain Stimulation: A Multicenter Survey. Front Neurol. 2020 Dec 16;11:616550. doi: 10.3389/fneur.2020.616550. PMID: 33391174; PMCID: PMC7772207.

150: La Rocca G, Simboli GA, Vincenzoni F, Rossetti DV, Urbani A, Ius T, Della Pepa GM, Olivi A, Sabatino G, Desiderio C. Glioblastoma CUSA Fluid Protein Profiling: A Comparative Investigation of the Core and Peripheral Tumor Zones. Cancers (Basel). 2020 Dec 23;13(1):30. doi: 10.3390/cancers13010030. PMID: 33374813; PMCID: PMC7795841.

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168: Giordano M, Caccavella VM, Zaed I, Foglia Manzillo L, Montano N, Olivi A, Polli FM. Comparison between deep brain stimulation and magnetic resonance- guided focused ultrasound in the treatment of essential tremor: a systematic review and pooled analysis of functional outcomes. J Neurol Neurosurg Psychiatry. 2020 Dec;91(12):1270-1278. doi: 10.1136/jnnp-2020-323216. Epub 2020 Oct 14. PMID: 33055140.

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173: Arcelli A, Buwenge M, Macchia G, Bertini F, Guido A, Deodato F, Cilla S, Scotti V, Rosetto ME, Djan I, Parisi S, Mattiucci GC, Cellini F, Fiore M, Bonomo P, Belgioia L, Niespolo RM, Gabriele P, Di Marco M, Simoni N, Mazzarotto R, Morganti AG; AIRO (Italian Association of Radiation Oncology and Clinical Oncology) Gastrointestinal Study Group. Stereotactic body radiotherapy vs conventionally fractionated chemoradiation in locally advanced pancreatic cancer: A multicenter case-control study (PAULA-1). Cancer Med. 2020 Nov;9(21):7879-7887. doi: 10.1002/cam4.3330. Epub 2020 Sep 10. PMID: 32910549; PMCID: PMC7643643.

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189: Angileri FF, Sabatino G, Cavallo LM, Pessina F, Ius T, DE Divitiis O, Esposito F, Grimod G, Raffa G, Spena G, Cardali S, Esposito V, GermanÒ A, Maiuri F, Fontanella M, Cenzato M; Neuro-oncology Section of the Italian Society of Neurosurgery (SINch®). Natura non facit saltus: a phase 2 proposal to manage brain tumors cases from the Neuro-oncology section of the Italian Society of Neurosurgery (SINch®). J Neurosurg Sci. 2021 Feb;65(1):1-7. doi: 10.23736/S0390-5616.20.05054-7. Epub 2020 Jun 11. PMID: 32525292.

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