Idiopathic normal pressure hydrocephalus treatment

The most commonly used treatment of NPH is implantation of a ventriculoperitoneal shunt 1).

Shunt surgery has been established as the only durable and effective treatment for idiopathic normal pressure hydrocephalus

To maximise the benefits of shunt treatment, surgery should be performed soon after diagnosis 2).

The results of a prospective multicentre study on patients with iNPH diagnosed solely on clinical and radiological criteria support shunt surgery in patients presenting with symptoms and signs and MRI findings suggestive of iNPH 3).

Clinical decisions regarding CSF shunt should be individualized to each patient, with adequate consideration of the relative risks and benefits, including maximizing a healthy life expectancy 4).

see Ventriculoperitoneal shunt for idiopathic normal pressure hydrocephalus.

see Lumboperitoneal shunt for idiopathic normal pressure hydrocephalus.

see Endoscopic third ventriculostomy for idiopathic normal pressure hydrocephalus.

see Idiopathic normal pressure hydrocephalus treatment complications.

Reddy GK, Bollam P, Caldito G (2014) Long-term outcomes of ventriculoperitoneal shunt surgery in patients with hydrocephalus. World Neurosurg 81:404–410. 2013.01.096
Andrén K, Wikkelsø C, Tisell M, Hellström P. Natural course of idiopathic normal pressure hydrocephalus. J Neurol Neurosurg Psychiatry. 2013 Nov 29. doi: 10.1136/jnnp-2013-306117. [Epub ahead of print] PubMed PMID: 24292998.
Klinge P, Hellström P, Tans J, Wikkelsø C; European iNPH Multicentre Study Group. One-year outcome in the European multicentre study on iNPH. Acta Neurol Scand. 2012 Sep;126(3):145-53. doi: 10.1111/j.1600-0404.2012.01676.x. Epub 2012 May 10. PubMed PMID: 22571428.
Nakajima M, Kuriyama N, Miyajima M, Ogino I, Akiba C, Kawamura K, Kurosawa M, Watanabe Y, Fukushima W, Mori E, Kato T, Sugano H, Tange Y, Karagiozov K, Arai H. Background Risk Factors Associated with Shunt Intervention for Possible Idiopathic Normal Pressure Hydrocephalus: A Nationwide Hospital-Based Survey in Japan. J Alzheimers Dis. 2019 Mar 11. doi: 10.3233/JAD-180955. [Epub ahead of print] PubMed PMID: 30883349.
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