After subarachnoid hemorrhage delayed onset vasospasm can result in devastating ischemic stroke.
Ischemia results if blood flow to the brain is below 18 to 20 ml per 100 g per minute, and tissue death occurs if flow dips below 8 to 10 ml per 100 g per minute.
Ischemic stroke is a leading cause of mortality and morbidity worldwide, and atherosclerosis is one of the major risk factors for this neurologic deficit.
In brain tissue, a biochemical cascade known as the ischemic cascade is triggered when the tissue becomes ischemic, potentially resulting in damage to and death of brain cells.
Ischemic stroke is a major cause of death and long-term disability worldwide.
Ischemic Stroke (Emergency Management in Neurology) By Giuseppe D'Aliberti, Marco Longoni, Valentina Oppo, Valentina Perini, Luca Valvassori, Simone Vidale, Cristina Motto