Born 1947 is a Finnish neurosurgeon, chairman and professor of the neurosurgery department in Helsinki University Hospital, Töölö.

He has a special interest in cerebrovascular diseases that are surgically amenable, especially aneurysms and AVMs. He has published extensively and is widely cited within this particular domain of neurosurgery.

1973 Medical Doctor (MD) 1979 Doctor of Medical Science (PhD) 1998 Professor in Neurosurgery

Specialization 1979 Specialization in Neurosurgery 1987 Associate Professor

1979-1983 Senior consultant in neurosurgical departments (Helsinki, Kuopio and Uppsala) 1983-1991 Assistant Chief Physician, Neurosurgery Department, Kuopio University Hospital 1991-1992 Chief Physician, Neurosurgery Department, Kuopio University Hospital 1992-1993 Research and Teaching Fellow, Neurosurgery Department, University of Miami 1993-1997 Chief Physician of Neurosurgery Department, Kuopio University Hospital 1997 Chairman, Department of Neurosurgery in Helsinki University Hospital, Töölö

Memberships in scientific advisory boards 1999- Member of International Advisory Board, Neurosurgery 1999-2008 Member of International Advisory Board, Surgical Neurology 2002 Member of International Advisory Board, Zentralblatt für Neurochirurgie 2008- Associate Editor, Surgical Neurology

Supervisor for 8 doctoral dissertations Co-supervisor for 5 doctoral dissertations General Secretary for 2 International Congresses: 40th Annual Meeting of the Scandinavian Neurosurgical Society, Kuopio 1989 and EANS Winter Meeting Kuopio, Finland, 1994

Personal neurosurgical operative experience 14,000 operations including: cerebral aneurysm >4,000 patients intracranial AVM and DAVF >500 patients brain tumour >3,000 patients head injury >600 patients cervical spine >800 patients lumbar spine >300 patients spinal tumour >300 patients

1: Hernesniemi J, Korja M. At the Apex of Cerebrovascular Surgery-Basilar Tip Aneurysms. World Neurosurg. 2013 Aug 3. pii: S1878-8750(13)00926-1. doi: 10.1016/j.wneu.2013.07.112. [Epub ahead of print] PubMed PMID: 23920297.

2: Hernesniemi JA, Seppälä I, Lyytikäinen LP, Mononen N, Oksala N, Hutri-Kähönen N, Juonala M, Taittonen L, Smith EN, Schork NJ, Chen W, Srinivasan SR, Berenson GS, Murray SS, Laitinen T, Jula A, Kettunen J, Ripatti S, Laaksonen R, Viikari J, Kähönen M, Raitakari OT, Lehtimäki T. Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey–a meta-analysis of three independent studies. PLoS One. 2012;7(1):e28931. doi: 10.1371/journal.pone.0028931. Epub 2012 Jan 25. PubMed PMID: 22295058; PubMed Central PMCID: PMC3266236.

3: Hernesniemi J, Niemelä M. Clipping of a ruptured aneurysm with clot removal in one session: still gold standard of treatment. World Neurosurg. 2010 Dec;74(6):579-80. doi: 10.1016/j.wneu.2010.07.013. PubMed PMID: 21492623.

4: Hernesniemi JA, Anttila K, Nieminen T, Kähönen M, Mononen N, Nikus K, Turjanmaa V, Viik J, Lehtinen R, Lehtimäki T. IL-18 gene polymorphism, cardiovascular mortality and coronary artery disease. Eur J Clin Invest. 2010 Nov;40(11):994-1001. doi: 10.1111/j.1365-2362.2010.02356.x. PubMed PMID: 20735470.

5: Hernesniemi J, Dashti R, Niemelä M, Romani R, Rinne J, Jääskeläinen JE. Microsurgical and angiographic anatomy of middle cerebral artery aneurysm. Neurosurgery. 2010 May;66(5):E1030. doi: 10.1227/NEU.0B013E3181D8CCAB. PubMed PMID: 20404680.

6: Hernesniemi JA, Heikkilä A, Raitakari OT, Kähönen M, Juonala M, Hutri-Kähönen N, Marniemi J, Viikari J, Lehtimäki T. Interleukin-18 gene polymorphism and markers of subclinical atherosclerosis. The Cardiovascular Risk in Young Finns Study. Ann Med. 2010 Apr;42(3):223-30. doi: 10.3109/07853891003769940. PubMed PMID: 20350254.

7: Hernesniemi J, Romani R, Lehecka M, Isarakul P, Dashti R, Celik O, Navratil O, Niemelä M, Laakso A. Present state of microneurosurgery of cerebral arteriovenous malformations. Acta Neurochir Suppl. 2010;107:71-6. doi: 10.1007/978-3-211-99373-6_11. Review. PubMed PMID: 19953374.

8: Hernesniemi JA, Karhunen PJ, Oksala N, Kähönen M, Levula M, Rontu R, Ilveskoski E, Kajander O, Goebeler S, Viiri LE, Hurme M, Lehtimäki T. Interleukin 18 gene promoter polymorphism: a link between hypertension and pre-hospital sudden cardiac death: the Helsinki Sudden Death Study. Eur Heart J. 2009 Dec;30(23):2939-46. doi: 10.1093/eurheartj/ehp316. Epub 2009 Aug 17. PubMed PMID: 19687159.

9: Hernesniemi J, Romani R, Albayrak BS, Lehto H, Dashti R, Ramsey C 3rd, Karatas A, Cardia A, Navratil O, Piippo A, Fujiki M, Toninelli S, Niemelä M. Microsurgical management of pineal region lesions: personal experience with 119 patients. Surg Neurol. 2008 Dec;70(6):576-83. doi: 10.1016/j.surneu.2008.07.019. PubMed PMID: 19055952.

10: Hernesniemi JA, Dashti R, Juvela S, Väärt K, Niemelä M, Laakso A. Natural history of brain arteriovenous malformations: a long-term follow-up study of risk of hemorrhage in 238 patients. Neurosurgery. 2008 Nov;63(5):823-9; discussion 829-31. doi: 10.1227/01.NEU.0000330401.82582.5E. PubMed PMID: 19005371.

11: Hernesniemi J, Romani R, Niemelä M. Skull base and aneurysm surgery. Surg Neurol. 2009 Jan;71(1):30-1. doi: 10.1016/j.surneu.2008.03.003. Epub 2008 Jun 2. PubMed PMID: 18514291.

12: Hernesniemi J, Dashti R, Mateo O, Cancela P, Karatas A, Niemelä M. Historical landmarks in vascular neurosurgery “On July 10th 2006, at the 70th Anniversary of the Department of Neurosurgery of Zürich Medical School”. Acta Neurochir Suppl. 2008;103:131-7. PubMed PMID: 18496959.

13: Hernesniemi J, Dashti R, Lehecka M, Niemelä M, Rinne J, Lehto H, Ronkainen A, Koivisto T, Jääskeläinen JE. Microneurosurgical management of anterior communicating artery aneurysms. Surg Neurol. 2008 Jul;70(1):8-28; discussion 29. doi: 10.1016/j.surneu.2008.01.056. Epub 2008 May 2. Review. PubMed PMID: 18452980.

14: Hernesniemi J, Romani R, Dashti R, Albayrak BS, Savolainen S, Ramsey C 3rd, Karatas A, Lehto H, Navratil O, Niemelä M. Microsurgical treatment of third ventricular colloid cysts by interhemispheric far lateral transcallosal approach–experience of 134 patients. Surg Neurol. 2008 May;69(5):447-53; discussion 453-6. doi: 10.1016/j.surneu.2007.11.005. Epub 2008 Mar 4. PubMed PMID: 18295836.

15: Hernesniemi JA, Raitakari OT, Kähönen M, Juonala M, Hutri-Kähönen N, Marniemi J, Viikari J, Lehtimäki T. Toll-like receptor 4 gene (Asp299Gly) polymorphism associates with carotid artery elasticity. The cardiovascular risk in young Finns study. Atherosclerosis. 2008 May;198(1):152-9. Epub 2007 Nov 9. PubMed PMID: 17996871.

16: Hernesniemi JA, Karhunen PJ, Rontu R, Ilveskoski E, Kajander O, Goebeler S, Viiri LE, Pessi T, Hurme M, Lehtimäki T. Interleukin-18 promoter polymorphism associates with the occurrence of sudden cardiac death among Caucasian males: the Helsinki Sudden Death Study. Atherosclerosis. 2008 Feb;196(2):643-9. Epub 2007 Aug 31. PubMed PMID: 17765248.

17: Hernesniemi J, Lehtimäki T, Rontu R, Islam MS, Eklund C, Mikkelsson J, Ilveskoski E, Kajander O, Goebeler S, Viiri LE, Hurme M, Karhunen PJ. Toll-like receptor 4 polymorphism is associated with coronary stenosis but not with the occurrence of acute or old myocardial infarctions. Scand J Clin Lab Invest. 2006;66(8):667-75. PubMed PMID: 17101559.

18: Hernesniemi J, Niemelä M, Dashti R, Karatas A, Kivipelto L, Ishii K, Rinne J, Ronkainen A, Peláez JG, Koivisto T, Kivisaari R, Shen H, Lehecka M, Frösen J, Piippo A, Avci E, Jääskeläinen JE. Principles of microneurosurgery for safe and fast surgery. Surg Technol Int. 2006;15:305-10. Review. PubMed PMID: 17029189.

19: Hernesniemi J, Karatas A, Niemelä M, Ishii K, Shen H, Kivisaari R, Rinne J, Lehecka M, Kivipelto L. Aneurysms of the vertebral artery (VA). Zentralbl Neurochir. 2005 Nov;66(4):223-9; author reply 230. PubMed PMID: 16317606.

20: Hernesniemi J, Ishii K, Karatas A, Kivipelto L, Niemelä M, Nagy L, Shen H. Surgical technique to retract the tentorial edge during subtemporal approach: technical note. Neurosurgery. 2005 Oct;57(4 Suppl):E408; discussion E408. PubMed PMID: 16234661.

21: Hernesniemi J, Karatas A, Ishii K, Niemelä M. Anteroinferior cerebellar artery aneurysms: surgical approaches and outcomes–a review of 34 cases. Neurosurgery. 2005 Sep;57(3):E601; author reply E601. Review. PubMed PMID: 16145515.

22: Hernesniemi J, Niemelä M, Karatas A, Kivipelto L, Ishii K, Rinne J, Ronkainen A, Koivisto T, Kivisaari R, Shen H, Lehecka M, Frösen J, Piippo A, Jääskeläinen JE. Some collected principles of microneurosurgery: simple and fast, while preserving normal anatomy: a review. Surg Neurol. 2005 Sep;64(3):195-200. Review. PubMed PMID: 16099243.

23: Hernesniemi J, Ishii K, Niemelä M, Kivipelto L, Fujiki M, Shen H. Subtemporal approach to basilar bifurcation aneurysms: advanced technique and clinical experience. Acta Neurochir Suppl. 2005;94:31-8. PubMed PMID: 16060238.

24: Hernesniemi J, Ishii K, Niemelä M, Smrcka M, Kivipelto L, Fujiki M, Shen H. Lateral supraorbital approach as an alternative to the classical pterional approach. Acta Neurochir Suppl. 2005;94:17-21. PubMed PMID: 16060236.

25: Hernesniemi J, Koivisto T. Comments on “The impact of the International Subarachnoid Aneurysm Treatment Trial (ISAT) on neurosurgical practice”. Acta Neurochir (Wien). 2004 Feb;146(2):203-8. Epub 2004 Jan 30. PubMed PMID: 14963759.

26: Hernesniemi J, Rinne J. Multiple aneurysms. Surg Neurol. 2003 Aug;60(2):136-7. PubMed PMID: 12900120.

27: Hernesniemi J. Clinical and radiographic outcome in the management of posterior circulation aneurysms by use of direct surgical or endovascular techniques. Neurosurgery. 2003 Jun;52(6):1505-6; author reply 1506. PubMed PMID: 12800837.

28: Hernesniemi J. Distal PICA aneurysms. J Neurosurg. 2003 May;98(5):1144; author reply 1144. PubMed PMID: 12744383.

29: Hernesniemi J. The sizer-dissector for aneurysm clip selection: technical note. Neurosurgery. 2003 May;52(5):1241; author reply 1241. PubMed PMID: 12728947.

30: Hernesniemi J. Posterior fossa aneurysms. J Neurosurg. 2002 Mar;96(3):638-40. PubMed PMID: 11883857.

31: Hernesniemi J. Mechanisms to improve treatment standards in neurosurgery, cerebral aneurysm surgery as example. Acta Neurochir Suppl. 2001;78:127-34. PubMed PMID: 11840706.

32: Hernesniemi J. Double aneurysms at distal basilar artery: report of nine cases. Neurosurgery. 2001 Jul;49(1):229-31. PubMed PMID: 11440453.

33: Hernesniemi J, Leivo S. Management outcome in third ventricular colloid cysts in a defined population: a series of 40 patients treated mainly by transcallosal microsurgery. Surg Neurol. 1996 Jan;45(1):2-14. PubMed PMID: 9190693.

34: Hernesniemi J, Rinne J, Vihavainen M, Savolainen S. [Cervical disc herniation]. Duodecim. 1995;111(21):2084-9. Review. Finnish. PubMed PMID: 9841167.

35: Hernesniemi J. [The treatment of intracranial arteriovenous malformations]. Duodecim. 1995;111(21):2039-46. Review. Finnish. PubMed PMID: 9841161.

36: Hernesniemi J, Vapalahti M, Niskanen M, Tapaninaho A, Kari A, Luukkonen M, Puranen M, Saari T, Rajpar M. One-year outcome in early aneurysm surgery: a 14 years experience. Acta Neurochir (Wien). 1993;122(1-2):1-10. PubMed PMID: 8333298.

37: Hernesniemi J, Tapaninaho A, Vapalahti M, Niskanen M, Kari A, Luukkonen M. Saccular aneurysms of the distal anterior cerebral artery and its branches. Neurosurgery. 1992 Dec;31(6):994-8; discussion 998-9. PubMed PMID: 1470334.

38: Hernesniemi J, Vapalahti M, Niskanen M, Kari A. Management outcome for vertebrobasilar artery aneurysms by early surgery. Neurosurgery. 1992 Nov;31(5):857-61; discussion 861-2. PubMed PMID: 1279451.

39: Hernesniemi J. Arteriovenous malformations of the vein of Galen: report of three microsurgically treated cases. Surg Neurol. 1991 Dec;36(6):465-9. PubMed PMID: 1759188.

40: Hernesniemi J, Keränen T. Microsurgical treatment of arteriovenous malformations of the brain in a defined population. Surg Neurol. 1990 Jun;33(6):384-90. PubMed PMID: 2349534.

41: Hernesniemi J, Keränen T. Long-term outcome after surgery for spasmodic torticollis. Acta Neurochir (Wien). 1990;103(3-4):128-30. PubMed PMID: 2399839.

42: Hernesniemi J. Anterior hemispheric approach. Surg Neurol. 1986 Mar;25(3):304. PubMed PMID: 3945913.

43: Hernesniemi J, Keränen T, Puranen M, Rajpar M. [Surgical treatment of arteriovenous malformations of the brain]. Duodecim. 1986;102(19):1371-80. Finnish. PubMed PMID: 3780478.

44: Hernesniemi J, Valtonen S, Männikkö A. [Can mortality in severe traumatic brain damage be generally reduced?]. Zentralbl Neurochir. 1986;47(2):99-104. German. PubMed PMID: 3765968.

45: Hernesniemi J, Troupp H. A retrospective study on the effects of low and high doses of betamethasone on severe closed head injury. Acta Neurochir (Wien). 1980;51(3-4):149-55. PubMed PMID: 7368991.

46: Hernesniemi J. Outcome following head injuries in the aged. Acta Neurochir (Wien). 1979;49(1-2):67-79. PubMed PMID: 525464.

47: Hernesniemi J. Penetrating craniocerebral gunshot wounds in civilians. Acta Neurochir (Wien). 1979;49(3-4):199-205. PubMed PMID: 517178.

48: Hernesniemi J. Outcome following acute subdural haematoma. Acta Neurochir (Wien). 1979;49(3-4):191-8. PubMed PMID: 517177.

49: Hernesniemi J, Troupp H. A clinical retrospective and a double-blind study of betamethasone in severe closed brain injuries [proceedings]. Acta Neurochir Suppl (Wien). 1979;28(2):499. PubMed PMID: 290243.

50: Hernesniemi J, Laitinen L. [Late results of surgical treatment of spasmodic torticollis]. Neurochirurgie. 1977 Jul 30;23(2):123-31. French. PubMed PMID: 917182.

51: Hernesniemi J, Laitinen L. No specific thalamic influence on cell composition, sugar or electrolytes of peripheral blood. Appl Neurophysiol. 1976-1977;39(1):43-9. PubMed PMID: 1052285.

52: Hernesniemi J, Kawana E, Bruppacher H, Sandri C. Afferent connections of the subfornical organ and of the supraoptic crest. Acta Anat (Basel). 1972;81(3):321-36. PubMed PMID: 5028036.

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