Knosp Grade 3B
Latest articles
Below the intracavernous internal carotid artery into the inferior cavernous sinus compartment The tumor extends to the lateral line inferiorly (under ICA) 1).
A significantly higher rate of remission can be achieved in grade 3A than in grade 3B and grade 4 adenomas. Therefore, the distinction into grades 3A, 3B, and 4 is of importance for the prediction of adenoma invasion and surgical treatment considerations 2)
1)
Micko AS, Wöhrer A, Wolfsberger S, Knosp E. Invasion of the cavernous sinus
space in pituitary adenomas: endoscopic verification and its correlation with an
MRI-based classification. J Neurosurg. 2015 Apr;122(4):803-11. doi:
10.3171/2014.12.JNS141083. Epub 2015 Feb 6. PubMed PMID: 25658782.
2)
Micko A, Oberndorfer J, Weninger WJ, Vila G, Höftberger R, Wolfsberger S, Knosp E. Challenging Knosp high-grade pituitary adenomas. J Neurosurg. 2019 May 31;132(6):1739-1746. doi: 10.3171/2019.3.JNS19367. PMID: 31151112.