● may be primary (Primary central nervous system lymphoma) or secondary (pathologically identical)

● suspected with homogeneously enhancing lesion(s) in the central gray matter or corpus callosum (on MRI or CT) especially in AIDS patients

● may present with multiple cranial-nerve palsies

● diagnosis highly likely if tumor seen in conjunction with uveitis

● very responsive initially to steroids → short-lived disappearance (“ghost tumors”)

● treatment: usually XRT ± chemotherapy. Role of neurosurgery usually limited to biopsy and/or placement of ventricular access reservoir for chemotherapy

● risk factors: immunosuppression (AIDS, transplants), Epstein-Barr virus, collagen vascular diseases

  • lymphoma.txt
  • Last modified: 2023/03/23 09:04
  • by administrador