meningioma_differential_diagnosis

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meningioma_differential_diagnosis [2021/11/25 11:06]
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meningioma_differential_diagnosis [2021/12/02 23:27] (current)
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 4. [[Rosai-Dorfman disease]]: especially if extracranial lesions are also identified. A connective tissue 4. [[Rosai-Dorfman disease]]: especially if extracranial lesions are also identified. A connective tissue
 disorder with sinus histiocytosis and massive painless lymphadenopathy (most have cervical lymphadenopathy). Usually in young adults. Isolated intracranial involvement is rare. MRI: dural- based enhancing mass with signal characteristics similar to meningioma, may have a dural tail. Most common intracranial locations: cerebral convexities, parasagittal, suprasellar, cavernous sinus. Pathology: dense fibro collagenous connective tissue with spindle cells and lymphocytic infiltration, stains for CD68 & S-100. Histiocytic proliferation without malignancy. Foamy histiocytes are characteristic. Surgery and immunosuppressive therapy not effective. Low-dose XRT may be the best option. disorder with sinus histiocytosis and massive painless lymphadenopathy (most have cervical lymphadenopathy). Usually in young adults. Isolated intracranial involvement is rare. MRI: dural- based enhancing mass with signal characteristics similar to meningioma, may have a dural tail. Most common intracranial locations: cerebral convexities, parasagittal, suprasellar, cavernous sinus. Pathology: dense fibro collagenous connective tissue with spindle cells and lymphocytic infiltration, stains for CD68 & S-100. Histiocytic proliferation without malignancy. Foamy histiocytes are characteristic. Surgery and immunosuppressive therapy not effective. Low-dose XRT may be the best option.
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 +see also [[Parasagittal Meningioma Differential Diagnosis]].
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 The differential for dural lesions is extensive and includes The differential for dural lesions is extensive and includes
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