Meningitis treatment

In 2017, the Infectious Diseases Society of America (IDSA) published guidelines for healthcare-associated ventriculitis treatment and meningitis treatment 1).

The most important prognostic factor is the appropriate choice of pathogen-specific antibacterial therapy:

Antibiotics for specific organisms in meningitis Specific antibiotics

Route is IV unless specified otherwise.

1. Streptococcus pneumoniae: Penicillin G (PCN G)

if MIC ≤ 0.06:PCNG or ampicillin,alternative:third generation cephalosporin(ceftriaxone)

if MIC ≥0.12:third generation cephalosporin (ceftriaxone) if cephalosporin resistance: vancomycin


meningitidis: PCN G

ifMIC ≤0.1 PCN G or ampicillin

if MIC ≥0.1:third generation cephalosporin (ceftriaxone) alternative: moxifloxacin, meropenem

Tunkel AR, Hasbun R, Bhimraj A, et al. 2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis. 2017;64(6):e34-e65. doi:10.1093/cid/ciw861
  • meningitis_treatment.txt
  • Last modified: 2022/02/15 08:48
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