Based on level 2 evidence, RS is an efficacious treatment to control seizures in MTLE, possibly resulting in superior neuropsychological outcomes and quality of life metrics in selected subjects compared to microsurgery. RS has a better risk-benefit ratio for small hypothalamic hamartomas compared to surgical methods Delayed therapeutic effect resulting in ongoing seizures is associated with morbidity and mortality risk. Lack of level 1 evidence precludes the formation of guidelines at present 1).

McGonigal A, Sahgal A, De Salles A, Hayashi M, Levivier M, Ma L, Martinez R, Paddick I, Ryu S, Slotman BJ, RĂ©gis J. Radiosurgery for epilepsy: Systematic review and International Stereotactic Radiosurgery Society (ISRS) practice guideline. Epilepsy Res. 2017 Sep 19. pii: S0920-1211(17)30408-4. doi: 10.1016/j.eplepsyres.2017.08.016. [Epub ahead of print] Review. PubMed PMID: 28939289.
  • mesial_temporal_lobe_epilepsy_radiosurgery.txt
  • Last modified: 2017/09/26 16:49
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