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mitochondrial_dysfunction [2020/01/17 11:16]
administrador
mitochondrial_dysfunction [2020/02/18 18:25] (current)
administrador
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 ====== Mitochondrial dysfunction ====== ====== Mitochondrial dysfunction ======
 +
 +Mitochondrial dysregulation is a pivotal hallmark of aging-related disorders. Although there is a considerable understanding of the molecular counteracting responses toward damaged [[mitochondria]],​ the molecular underpinnings connecting the abnormal aggregation of mitochondrial precursor protein fragments and abrogation of mitochondrial import machinery are far from clear. Proteasomal-dependent degradation was unveiled as a pivotal fine-tuner of TOM machinery-dependent mitochondrial import
 +((Eldeeb MA, Ragheb MA, Esmaili M. How does protein degradation regulate TOM
 +machinery-dependent mitochondrial import? Curr Genet. 2020 Feb 14. doi:
 +10.1007/​s00294-020-01056-0. [Epub ahead of print] Review. PubMed PMID: 32060627.
 +)).
 +----
 +
  
 [[Mitochondria]]l dysfunction occurs when the mitochondria do not work as well as they should due to another disease or condition. [[Mitochondria]]l dysfunction occurs when the mitochondria do not work as well as they should due to another disease or condition.
mitochondrial_dysfunction.txt · Last modified: 2020/02/18 18:25 by administrador