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Nasopharyngeal carcinoma

Epstein-Barr virus DNA level is significantly correlated to the outcomes of patients with Nasopharyngeal carcinoma (NPC) 1).

The fossa of Rosenmüller, also known as the posterolateral recess, is the most common site of origin for nasopharyngeal carcinoma

Differential diagnosis

Case reports

A nasopharyngeal carcinoma arose in a 52-year-old patient and occupied the right middle skull base extending to the ICA. We first identified and dissected the ICA from the posterolateral part of the tumor using a transcervical approach. Then, the tumor was approached and removed by an orbitozygomatic technique with hemifacial dismasking. The surgical defect was filled using a temporal muscle flap, which was divided into two parts according to the blood supply from either the anterior or the posterior deep temporal artery.

The postoperative course was uneventful and favorable cosmetic results were obtained. The patient has been free of carcinoma for more than 40 months after the surgery.

This new combined approach might be a good option for selected patients with nasopharyngeal tumors 2).

Zhang J, Shu C, Song Y, Li Q, Huang J, Ma X. Epstein-Barr virus DNA level as a novel prognostic factor in nasopharyngeal carcinoma: A meta-analysis. Medicine (Baltimore). 2016 Oct;95(40):e5130. PubMed PMID: 27749596.
Masuda M, Fukushima J, Fujimura A, Uryu H. Combined transcervical and orbitozygomatic approach for the removal of a nasopharyngeal adenocarcinoma. Auris Nasus Larynx. 2015 Jul 9. pii: S0385-8146(15)00164-9. doi: 10.1016/j.anl.2015.06.006. [Epub ahead of print] PubMed PMID: 26165630.
nasopharyngeal_carcinoma.txt · Last modified: 2016/10/18 16:03 (external edit)