non-small_cell_lung_cancer_intracranial_metastases

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non-small_cell_lung_cancer_intracranial_metastases [2021/05/09 10:19]
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non-small_cell_lung_cancer_intracranial_metastases [2021/06/21 12:00] (current)
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 ====== Non-Small-cell lung cancer intracranial metastases ====== ====== Non-Small-cell lung cancer intracranial metastases ======
-====Epidemiology==== 
-[[Lung cancer]] is the leading cause of cancer mortality worldwide, accounting for 1.38 million annual deaths, representing 18.2% of total deaths from [[cancer]]  
-((Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer 
-statistics. CA Cancer J Clin. 2011 Mar-Apr;61(2):69-90. doi: 10.3322/caac.20107.  
-Epub 2011 Feb 4. Erratum in: CA Cancer J Clin. 2011 Mar-Apr;61(2):134. PubMed 
-PMID: 21296855. 
-)). 
  
-Among those, approximately 7.4% of [[non-Small-cell lung cancer]] (NSCLC) patients will have brain metastases (BM) at presentation +see [[Non-Small-cell lung cancer intracranial metastases]]
-((Schuette W. Treatment of brain metastases from lung cancer: chemotherapy. Lung +
-Cancer. 2004 Aug;45 Suppl 2:S253-7. Review. PubMed PMID: 15552807. +
-)) +
-, and between 20–40% of [[Non-Small-cell lung cancer]] (NSCLC) patients will develop [[intracranial metastases]]  +
-((Brower JV, Robins HI. Erlotinib for the treatment of brain metastases in +
-non-Small-cell lung cancer. Expert Opin Pharmacother. 2016;17(7):1013-21. doi: +
-10.1517/14656566.2016.1165206. Epub 2016 Mar 30. Review. PubMed PMID: 26967582. +
-)) +
-((Zhao J, Chen M, Zhong W, Zhang L, Li L, Xiao Y, Nie L, Hu P, Wang M. +
-Cerebrospinal fluid concentrations of gefitinib in patients with lung +
-adenocarcinoma. Clin Lung Cancer. 2013 Mar;14(2):188-93. doi: +
-10.1016/j.cllc.2012.06.004. Epub 2012 Jul 28. PubMed PMID: 22846582. +
-)). +
- +
-see also [[Anaplastic lymphoma kinase non-Small-cell lung cancer intracranial metastases]] +
- +
-===== Treatment ===== +
-see [[Non-Small-cell lung cancer intracranial metastases treatment]]. +
- +
-===== Outcome ===== +
- +
-see [[Non Small-cell lung cancer intracranial metastases outcome]]. +
- +
-===== Case series ===== +
- +
-see [[Non Small-cell lung cancer intracranial metastases case series]].+
  
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