Phosphoinositide 3-kinase

Phosphatidylinositol-4,5-bisphosphate 3-kinase (also called phosphatidylinositide 3-kinases, phosphatidylinositol-3-kinases, PI 3-kinases, PI(3)Ks, PI-3Ks or by the HUGO official stem symbol for the gene family, PI3K(s)) are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

It plays a pivotal role in transmitting signals from cell surface receptors, such as growth factor receptors and cytokine receptors, to downstream signaling pathways that regulate important cellular functions.

see PI3K/AKT/mTOR pathway.

  • phosphoinositide_3-kinase.txt
  • Last modified: 2023/09/05 17:30
  • by administrador